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Peptide record

TPDB07028

Antibacterial Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB07028
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 13-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
ILPWKKPKKPKRR
Physicochemical Analysis
C80H139N25O14
ANDCEQGHMFSTYV
K
1675.14
12.45
7
0
3
+7
5.20
-1.992
60.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
5500
328.33
0
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
1
L
5
K
0
M
0
F
3
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 1 K: 5 M: 0 F: 0 P: 3 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
13
C80H139N25O14
1675.14
12.45
+7
5.20
-1.992
Evidence Records 1 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
>200 µg/mL
Hemolytic Cytotoxic
5% Hemolysis | >200 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Investigating the effects of positive charge and hydrophobicity on the cell selectivity, mechanism of action and anti-inflammatory activity of a Trp-rich antimicrobial peptide indolicidin | FEMS Microbiol Lett | 2009