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Peptide record

TPDB07021

Antibacterial Antifungal Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB07021
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
FLGELWNVAKSVF
Physicochemical Analysis
C74H108N16O18
RDCQHIMPTY
LFV
1509.77
6.94
1
1
8
-0
-1.69
0.800
112.31
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
5500
364.29
2
Residue Composition
number
1
A
0
R
1
N
0
D
0
C
1
E
0
Q
1
G
0
H
0
I
2
L
1
K
0
M
2
F
0
P
1
S
0
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 0 C: 0 E: 1 Q: 0 G: 1 H: 0 I: 0 L: 2 K: 1 M: 0 F: 2 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 2
Chemical Descriptors
13
C74H108N16O18
1509.77
6.94
-0
-1.69
0.800
Evidence Records 3 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
0% Hemolysis | 25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Novel designed VmCT1 analogs with increased antimicrobial activity. | Eur J Med Chem | 2017
Evidence 2 Activity

Activity

90% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
90% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Novel designed VmCT1 analogs with increased antimicrobial activity. | Eur J Med Chem | 2017
Evidence 3 Activity

Activity

MHC
Toxicity
25 µm
Hemolytic
Hemolytic_activity: [Ref.27912176] MHC=25µmol/L against human red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Eur J Med Chem. 2017 Jan 27 126:456-463.