Back to search

Peptide record

TPDB07016

Antibacterial Hemolysis Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB07016
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
ALWMTLLKKVLKA
Physicochemical Analysis
C73H127N17O15S1
RNDCEQGHIFPSY
L
1514.98
10.84
3
0
9
+3
-1.48
0.892
157.69
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
5500
363.04
1
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
4
L
3
K
1
M
0
F
0
P
0
S
1
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 4 K: 3 M: 1 F: 0 P: 0 S: 0 T: 1 W: 1 Y: 0 V: 1
Chemical Descriptors
13
C73H127N17O15S1
1514.98
10.84
+3
-1.48
0.892
Evidence Records 5 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
20±2 µM
Hemolytic Cytotoxic
50% Hemolysis | 20±2 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Physicochemical properties that enhance discriminative antibacterial activity of short dermaseptin derivatives. | Antimicrob Agents Chemother | 2006
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
17±1 µM
Hemolytic Cytotoxic
50% Hemolysis | 17±1 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Physicochemical properties that enhance discriminative antibacterial activity of short dermaseptin derivatives. | Antimicrob Agents Chemother | 2006
Evidence 3 Activity

Activity

50% Hemolysis
Toxicity
10±1 µM
Hemolytic Cytotoxic
50% Hemolysis | 10±1 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Physicochemical properties that enhance discriminative antibacterial activity of short dermaseptin derivatives. | Antimicrob Agents Chemother | 2006
Evidence 4 Activity

Activity

50% Hemolysis
Toxicity
7±1 µM
Hemolytic Cytotoxic
50% Hemolysis | 7±1 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Physicochemical properties that enhance discriminative antibacterial activity of short dermaseptin derivatives. | Antimicrob Agents Chemother | 2006
Evidence 5 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis