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Peptide record

TPDB07001

Antibacterial Antifungal Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB07001
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
ILPAKAPAAPARR
Physicochemical Analysis
C60H106N20O14
NDCEQGHMFSTWYV
A
1331.63
12.41
3
0
7
+3
2.24
-0.031
98.46
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
0
Residue Composition
number
5
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
1
L
1
K
0
M
0
F
3
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 5 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 1 K: 1 M: 0 F: 0 P: 3 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
13
C60H106N20O14
1331.63
12.41
+3
2.24
-0.031
Evidence Records 2 records
Evidence 1 Activity

Activity

1% Hemolysis
Toxicity
6800 µg/mL
Hemolytic Cytotoxic
1% Hemolysis | 6800 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The effects of tryptophan and hydrophobicity on the structure and bioactivity of novel indolicidin derivatives with promising pharmaceutical potential. | Org Biomol Chem | 2010
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 200 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Indolicidin analogs with broad-spectrum antimicrobial activity and low hemolytic activity | Peptides | 2020