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Peptide record

TPDB07000

Antibacterial Antifungal Hemolysis Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB07000
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
FVRWFSRFLGRIL
Physicochemical Analysis
C84H125N23O15
ANDCEQHKMPTY
RF
1697.06
12.70
3
0
8
+3
-4.03
0.700
112.31
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
5500
324.09
1
Residue Composition
number
0
A
3
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
2
L
0
K
0
M
3
F
0
P
1
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 2 K: 0 M: 0 F: 3 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
13
C84H125N23O15
1697.06
12.70
+3
-4.03
0.700
Evidence Records 6 records
Evidence 1 Activity

Activity

100% Hemolysis
Toxicity
24 µM
Hemolytic Cytotoxic
100% Hemolysis | 24 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-activity relationship, conformational and biological studies of temporin L analogues. | J Med Chem | 2011
Evidence 2 Activity

Activity

92% Hemolysis
Toxicity
12 µM
Hemolytic Cytotoxic
92% Hemolysis | 12 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-activity relationship, conformational and biological studies of temporin L analogues. | J Med Chem | 2011
Evidence 3 Activity

Activity

43% Hemolysis
Toxicity
6 µM
Hemolytic Cytotoxic
43% Hemolysis | 6 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-activity relationship, conformational and biological studies of temporin L analogues. | J Med Chem | 2011
Evidence 4 Activity

Activity

14% Hemolysis
Toxicity
3 µM
Hemolytic Cytotoxic
14% Hemolysis | 3 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-activity relationship, conformational and biological studies of temporin L analogues. | J Med Chem | 2011
Evidence 5 Activity

Activity

6% Hemolysis
Toxicity
1.5 µM
Hemolytic Cytotoxic
6% Hemolysis | 1.5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-activity relationship, conformational and biological studies of temporin L analogues. | J Med Chem | 2011
Evidence 6 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis