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Peptide record

TPDB06997

Antibacterial Antifungal Hemolysis Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB06997
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
FLPLIGRVLAGIL
Physicochemical Analysis
C68H116N16O14
NDCEQHKMSTWY
L
1381.77
11.05
1
0
9
+1
-2.81
2.008
210.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
1
A
1
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
2
I
4
L
0
K
0
M
1
F
1
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 2 L: 4 K: 0 M: 0 F: 1 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
13
C68H116N16O14
1381.77
11.05
+1
-2.81
2.008
Evidence Records 6 records
Evidence 1 Activity

Activity

70% Hemolysis
Toxicity
40 µM
Hemolytic Cytotoxic
70% Hemolysis | 40 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Alanine scanning analysis and structure-function relationships of the frog-skin antimicrobial peptide temporin-1Ta. | J Pept Sci | 2011
Evidence 2 Activity

Activity

14% Hemolysis
Toxicity
20 µM
Hemolytic Cytotoxic
14% Hemolysis | 20 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Alanine scanning analysis and structure-function relationships of the frog-skin antimicrobial peptide temporin-1Ta. | J Pept Sci | 2011
Evidence 3 Activity

Activity

6% Hemolysis
Toxicity
5 µM
Hemolytic Cytotoxic
6% Hemolysis | 5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Alanine scanning analysis and structure-function relationships of the frog-skin antimicrobial peptide temporin-1Ta. | J Pept Sci | 2011
Evidence 4 Activity

Activity

1% Hemolysis
Toxicity
2.5 µM
Hemolytic Cytotoxic
1% Hemolysis | 2.5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Alanine scanning analysis and structure-function relationships of the frog-skin antimicrobial peptide temporin-1Ta. | J Pept Sci | 2011
Evidence 5 Activity

Activity

0% Hemolysis
Toxicity
1.25 µM
Hemolytic Cytotoxic
0% Hemolysis | 1.25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Alanine scanning analysis and structure-function relationships of the frog-skin antimicrobial peptide temporin-1Ta. | J Pept Sci | 2011
Evidence 6 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis