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Peptide record

TPDB06985

Antibacterial Antifungal Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB06985
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia Antifungipept CAFPdb ToxinPred 3.0
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
NLKAIAALAKKLL
Physicochemical Analysis
C64H119N17O15
RDCEQGHMFPSTWYV
AL
1366.75
10.84
3
0
9
+3
0.16
0.900
180.77
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
0
0.00
1
Residue Composition
number
4
A
0
R
1
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
4
L
3
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 4 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 4 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
13
C64H119N17O15
1366.75
10.84
+3
0.16
0.900
Evidence Records 23 records
Evidence 1 Activity

Activity

MIC
Antibacterial
5 µM

Target

Staphylococcus aureus ATCC25923

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against Gram-positive S. aureus ATCC25923 (MIC 5 uM), E. faecalis ATCC29212 (MIC 5 uM), S. aureus IS 10# (MIC 10 uM), S. aureus IS 37# (MIC 10
Evidence 2 Activity

Activity

MIC
Antibacterial
5 µM

Target

Enterococcus faecalis ATCC29212

Source & Reference

dbAMP

Other

Active against Gram-positive S. aureus ATCC25923 (MIC 5 uM), E. faecalis ATCC29212 (MIC 5 uM), S. aureus IS 10# (MIC 10 uM), S. aureus IS 37# (MIC 10 uM), Gram-negative E. coli ATCC25
Evidence 3 Activity

Activity

MIC
Antibacterial
20 µM

Target

Escherichia coli ATCC25922

Source & Reference

dbAMP

Other

212 (MIC 5 uM), S. aureus IS 10# (MIC 10 uM), S. aureus IS 37# (MIC 10 uM), Gram-negative E. coli ATCC25922 (MIC 20 uM), E. cloacae ATCC13047 (MIC 10 uM), K. pneumoniae ATCC700603 (MIC 20 uM), B. pyocyaneus CM
Evidence 4 Activity

Activity

MIC
Antibacterial
10 µM

Target

Enterobacter cloacae ATCC13047

Source & Reference

dbAMP

Other

# (MIC 10 uM), S. aureus IS 37# (MIC 10 uM), Gram-negative E. coli ATCC25922 (MIC 20 uM), E. cloacae ATCC13047 (MIC 10 uM), K. pneumoniae ATCC700603 (MIC 20 uM), B. pyocyaneus CMCCB1010 (MIC 20 uM), P. aeruginosa
Evidence 5 Activity

Activity

MIC
Antibacterial
20 µM

Target

Klebsiella pneumoniae ATCC700603

Source & Reference

dbAMP

Other

IC 10 uM), Gram-negative E. coli ATCC25922 (MIC 20 uM), E. cloacae ATCC13047 (MIC 10 uM), K. pneumoniae ATCC700603 (MIC 20 uM), B. pyocyaneus CMCCB1010 (MIC 20 uM), P. aeruginosa ATCC27853 (MIC 40 uM), B. dysenteriae
Evidence 6 Activity

Activity

MIC
Antibacterial
20 µM

Target

B. pyocyaneus CMCCB1010

Source & Reference

dbAMP

Other

5922 (MIC 20 uM), E. cloacae ATCC13047 (MIC 10 uM), K. pneumoniae ATCC700603 (MIC 20 uM), B. pyocyaneus CMCCB1010 (MIC 20 uM), P. aeruginosa ATCC27853 (MIC 40 uM), B. dysenteriae (MIC 20 uM), E. coli IS 37# (MIC 5 u
Evidence 7 Activity

Activity

MIC
Antibacterial
40 µM

Target

Pseudomonas aeruginosa ATCC27853

Source & Reference

dbAMP

Other

7 (MIC 10 uM), K. pneumoniae ATCC700603 (MIC 20 uM), B. pyocyaneus CMCCB1010 (MIC 20 uM), P. aeruginosa ATCC27853 (MIC 40 uM), B. dysenteriae (MIC 20 uM), E. coli IS 37# (MIC 5 uM), E. coli IS 117# (MIC 20 uM), E. c
Evidence 8 Activity

Activity

MIC
Antibacterial
20 µM

Target

B. dysenteriae

Source & Reference

dbAMP

Other

03 (MIC 20 uM), B. pyocyaneus CMCCB1010 (MIC 20 uM), P. aeruginosa ATCC27853 (MIC 40 uM), B. dysenteriae (MIC 20 uM), E. coli IS 37# (MIC 5 uM), E. coli IS 117# (MIC 20 uM), E. coli IS 218# (MIC 10 uM), P.
Evidence 9 Activity

Activity

MIC
Antibacterial
10 µM

Target

Candida albicans ATCC2002

Source & Reference

dbAMP

Other

# (MIC 10 uM), P. aeruginosa IS 350# (MIC 10 uM), K. pneumoniae IS 59# (MIC 10 uM), fungi C. albicans ATCC2002 (MIC 10 uM), C. albicans ATCC90028 (MIC 10 uM), and C. parapsilosis ATCC22019 (MIC 40 uM). Updated 7/
Evidence 10 Activity

Activity

MIC
Antibacterial
10 µM

Target

Candida albicans ATCC90028

Source & Reference

dbAMP

Other

0# (MIC 10 uM), K. pneumoniae IS 59# (MIC 10 uM), fungi C. albicans ATCC2002 (MIC 10 uM), C. albicans ATCC90028 (MIC 10 uM), and C. parapsilosis ATCC22019 (MIC 40 uM). Updated 7/2021
Evidence 11 Activity

Activity

MIC
Antibacterial
40 µM

Target

C. parapsilosis ATCC22019

Source & Reference

dbAMP

Other

IC 10 uM), fungi C. albicans ATCC2002 (MIC 10 uM), C. albicans ATCC90028 (MIC 10 uM), and C. parapsilosis ATCC22019 (MIC 40 uM). Updated 7/2021
Evidence 12 Activity

Activity

MIC
Antifungal
5 µM

Target

Staphylococcus aureus ATCC25923

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against Gram-positive S. aureus ATCC25923 (MIC 5 uM), E. faecalis ATCC29212 (MIC 5 uM), S. aureus IS 10# (MIC 10 uM), S. aureus IS 37# (MIC 10
Evidence 13 Activity

Activity

MIC
Antifungal
5 µM

Target

Enterococcus faecalis ATCC29212

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against Gram-positive S. aureus ATCC25923 (MIC 5 uM), E. faecalis ATCC29212 (MIC 5 uM), S. aureus IS 10# (MIC 10 uM), S. aureus IS 37# (MIC 10 uM), Gram-negative E. coli ATCC25
Evidence 14 Activity

Activity

MIC
Antifungal
20 µM

Target

Escherichia coli ATCC25922

Source & Reference

dbAMP CAFPdb Antifungipept

Other

212 (MIC 5 uM), S. aureus IS 10# (MIC 10 uM), S. aureus IS 37# (MIC 10 uM), Gram-negative E. coli ATCC25922 (MIC 20 uM), E. cloacae ATCC13047 (MIC 10 uM), K. pneumoniae ATCC700603 (MIC 20 uM), B. pyocyaneus CM
Evidence 15 Activity

Activity

MIC
Antifungal
10 µM

Target

Enterobacter cloacae ATCC13047

Source & Reference

dbAMP CAFPdb Antifungipept

Other

# (MIC 10 uM), S. aureus IS 37# (MIC 10 uM), Gram-negative E. coli ATCC25922 (MIC 20 uM), E. cloacae ATCC13047 (MIC 10 uM), K. pneumoniae ATCC700603 (MIC 20 uM), B. pyocyaneus CMCCB1010 (MIC 20 uM), P. aeruginosa
Evidence 16 Activity

Activity

MIC
Antifungal
20 µM

Target

Klebsiella pneumoniae ATCC700603

Source & Reference

dbAMP CAFPdb Antifungipept

Other

IC 10 uM), Gram-negative E. coli ATCC25922 (MIC 20 uM), E. cloacae ATCC13047 (MIC 10 uM), K. pneumoniae ATCC700603 (MIC 20 uM), B. pyocyaneus CMCCB1010 (MIC 20 uM), P. aeruginosa ATCC27853 (MIC 40 uM), B. dysenteriae
Evidence 17 Activity

Activity

MIC
Antifungal
20 µM

Target

B. pyocyaneus CMCCB1010

Source & Reference

dbAMP CAFPdb Antifungipept

Other

5922 (MIC 20 uM), E. cloacae ATCC13047 (MIC 10 uM), K. pneumoniae ATCC700603 (MIC 20 uM), B. pyocyaneus CMCCB1010 (MIC 20 uM), P. aeruginosa ATCC27853 (MIC 40 uM), B. dysenteriae (MIC 20 uM), E. coli IS 37# (MIC 5 u
Evidence 18 Activity

Activity

MIC
Antifungal
40 µM

Target

Pseudomonas aeruginosa ATCC27853

Source & Reference

dbAMP CAFPdb Antifungipept

Other

7 (MIC 10 uM), K. pneumoniae ATCC700603 (MIC 20 uM), B. pyocyaneus CMCCB1010 (MIC 20 uM), P. aeruginosa ATCC27853 (MIC 40 uM), B. dysenteriae (MIC 20 uM), E. coli IS 37# (MIC 5 uM), E. coli IS 117# (MIC 20 uM), E. c
Evidence 19 Activity

Activity

MIC
Antifungal
20 µM

Target

B. dysenteriae

Source & Reference

dbAMP CAFPdb Antifungipept

Other

03 (MIC 20 uM), B. pyocyaneus CMCCB1010 (MIC 20 uM), P. aeruginosa ATCC27853 (MIC 40 uM), B. dysenteriae (MIC 20 uM), E. coli IS 37# (MIC 5 uM), E. coli IS 117# (MIC 20 uM), E. coli IS 218# (MIC 10 uM), P.
Evidence 20 Activity

Activity

MIC
Antifungal
10 µM

Target

Candida albicans ATCC2002

Source & Reference

dbAMP CAFPdb Antifungipept

Other

# (MIC 10 uM), P. aeruginosa IS 350# (MIC 10 uM), K. pneumoniae IS 59# (MIC 10 uM), fungi C. albicans ATCC2002 (MIC 10 uM), C. albicans ATCC90028 (MIC 10 uM), and C. parapsilosis ATCC22019 (MIC 40 uM). Updated 7/
Evidence 21 Activity

Activity

MIC
Antifungal
10 µM

Target

Candida albicans ATCC90028

Source & Reference

dbAMP CAFPdb Antifungipept

Other

0# (MIC 10 uM), K. pneumoniae IS 59# (MIC 10 uM), fungi C. albicans ATCC2002 (MIC 10 uM), C. albicans ATCC90028 (MIC 10 uM), and C. parapsilosis ATCC22019 (MIC 40 uM). Updated 7/2021
Evidence 22 Activity

Activity

MIC
Antifungal
40 µM

Target

C. parapsilosis ATCC22019

Source & Reference

dbAMP CAFPdb Antifungipept

Other

IC 10 uM), fungi C. albicans ATCC2002 (MIC 10 uM), C. albicans ATCC90028 (MIC 10 uM), and C. parapsilosis ATCC22019 (MIC 40 uM). Updated 7/2021
Evidence 23 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial peptides from the venom gland of the social wasp Vespa tropica. | Toxicon | 2013