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Peptide record

TPDB06983

Antibacterial Antifungal Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB06983
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP ToxinPred 3.0
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
FLPIVGKLLSGLF
Physicochemical Analysis
C71H114N14O15
ARNDCEQHMTWY
L
1403.77
10.10
1
0
8
+1
-3.15
1.723
172.31
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
1
I
4
L
1
K
0
M
2
F
1
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 1 L: 4 K: 1 M: 0 F: 2 P: 1 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
13
C71H114N14O15
1403.77
10.10
+1
-3.15
1.723
Evidence Records 9 records
Evidence 1 Activity

Activity

MIC
Antibacterial
37.5 µM

Target

Enterococcus faecalis 981

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
tive bacteria. R. rhodochrous X15 (IS) (MIC 9 uM), B. licheniformis X39 (IS) (MIC 19 uM), E. faecalis 981 (MIC 37.5 uM), S. carnosus KHS (IS)(MIC 19 uM), S.aureus ATCC 25923(MIC 150 uM), E.coli ATCC 25922 (MIC
Evidence 2 Activity

Activity

MIC
Antibacterial
150 µM

Target

S.aureus ATCC 25923

Source & Reference

dbAMP

Other

mis X39 (IS) (MIC 19 uM), E. faecalis 981 (MIC 37.5 uM), S. carnosus KHS (IS)(MIC 19 uM), S.aureus ATCC 25923(MIC 150 uM), E.coli ATCC 25922 (MIC >150 uM), P.aeruginosa CGMCC 1.50 (MIC >150 uM), P.aeruginosa 110
Evidence 3 Activity

Activity

MIC
Antibacterial
>150 µM

Target

E.coli ATCC 25922

Source & Reference

dbAMP

Other

alis 981 (MIC 37.5 uM), S. carnosus KHS (IS)(MIC 19 uM), S.aureus ATCC 25923(MIC 150 uM), E.coli ATCC 25922 (MIC >150 uM), P.aeruginosa CGMCC 1.50 (MIC >150 uM), P.aeruginosa 11053 (IS)(MIC >150 uM), K.pneumonia
Evidence 4 Activity

Activity

MIC
Antibacterial
>150 µM

Target

C.albicans ATCC 10231

Source & Reference

dbAMP

Other

24 (IS)(MIC >150 uM), P.faecalis X29 (IS)(MIC >150 uM), S.rubidaea X01 (IS)(MIC >150 uM), C.albicans ATCC 10231 (MIC >150 uM), Slime mold 090223 (IS) (MIC 150 uM). IS: Isolated strain.
Evidence 5 Activity

Activity

MIC
Antifungal
37.5 µM

Target

Enterococcus faecalis 981

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
tive bacteria. R. rhodochrous X15 (IS) (MIC 9 uM), B. licheniformis X39 (IS) (MIC 19 uM), E. faecalis 981 (MIC 37.5 uM), S. carnosus KHS (IS)(MIC 19 uM), S.aureus ATCC 25923(MIC 150 uM), E.coli ATCC 25922 (MIC
Evidence 6 Activity

Activity

MIC
Antifungal
150 µM

Target

S.aureus ATCC 25923

Source & Reference

dbAMP CAFPdb Antifungipept

Other

mis X39 (IS) (MIC 19 uM), E. faecalis 981 (MIC 37.5 uM), S. carnosus KHS (IS)(MIC 19 uM), S.aureus ATCC 25923(MIC 150 uM), E.coli ATCC 25922 (MIC >150 uM), P.aeruginosa CGMCC 1.50 (MIC >150 uM), P.aeruginosa 110
Evidence 7 Activity

Activity

MIC
Antifungal
>150 µM

Target

E.coli ATCC 25922

Source & Reference

dbAMP CAFPdb Antifungipept

Other

alis 981 (MIC 37.5 uM), S. carnosus KHS (IS)(MIC 19 uM), S.aureus ATCC 25923(MIC 150 uM), E.coli ATCC 25922 (MIC >150 uM), P.aeruginosa CGMCC 1.50 (MIC >150 uM), P.aeruginosa 11053 (IS)(MIC >150 uM), K.pneumonia
Evidence 8 Activity

Activity

MIC
Antifungal
>150 µM

Target

C.albicans ATCC 10231

Source & Reference

dbAMP CAFPdb Antifungipept

Other

24 (IS)(MIC >150 uM), P.faecalis X29 (IS)(MIC >150 uM), S.rubidaea X01 (IS)(MIC >150 uM), C.albicans ATCC 10231 (MIC >150 uM), Slime mold 090223 (IS) (MIC 150 uM). IS: Isolated strain.
Evidence 9 Activity

Activity

50% Hemolysis
Toxicity
150 µM
Hemolytic Cytotoxic
50% Hemolysis | 150 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Characterization of diverse antimicrobial peptides in skin secretions of Chungan torrent frog Amolops chunganensis | Peptides | 2012