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Peptide record

TPDB06960

Antibacterial Antifungal Hemolysis Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB06960
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP PD_Hemolysis
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
FLSTIWNGIKSLF
Physicochemical Analysis
C75H112N16O18
ARDCEQHMPYV
ILFS
1525.81
10.10
1
0
7
+1
-4.03
0.862
120.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
5500
360.46
4
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
0
E
0
Q
1
G
0
H
2
I
2
L
1
K
0
M
2
F
0
P
2
S
1
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 2 L: 2 K: 1 M: 0 F: 2 P: 0 S: 2 T: 1 W: 1 Y: 0 V: 0
Chemical Descriptors
13
C75H112N16O18
1525.81
10.10
+1
-4.03
0.862
Evidence Records 5 records
Evidence 1 Activity

Activity

EC50
Toxicity
376.70 µM
Cytotoxic
EC50 | 376.70 | µM | target cell: Baby Hamster Kidney cells BHK-21

Target

Baby Hamster Kidney cells BHK-21

Source & Reference

NA
DBAASP
Bioactivity of Natural and Engineered Antimicrobial Peptides from Venom of the Scorpions Urodacus yaschenkoi and U. manicatus. | Toxins (Basel) | 2017
Evidence 2 Activity

Activity

10% Hemolysis
Toxicity
2.94 µM
Hemolytic Cytotoxic
10% Hemolysis | 2.94 | µM | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Bioactivity of Natural and Engineered Antimicrobial Peptides from Venom of the Scorpions Urodacus yaschenkoi and U. manicatus. | Toxins (Basel) | 2017
Evidence 3 Activity

Activity

50% Hemolysis
Toxicity
24.48 µM
Hemolytic Cytotoxic
50% Hemolysis | 24.48 | µM | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Bioactivity of Natural and Engineered Antimicrobial Peptides from Venom of the Scorpions Urodacus yaschenkoi and U. manicatus. | Toxins (Basel) | 2017
Evidence 4 Activity

Activity

90% Hemolysis
Toxicity
200.83 µM
Hemolytic Cytotoxic
90% Hemolysis | 200.83 | µM | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Bioactivity of Natural and Engineered Antimicrobial Peptides from Venom of the Scorpions Urodacus yaschenkoi and U. manicatus. | Toxins (Basel) | 2017
Evidence 5 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis