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Peptide record

TPDB06957

Antibacterial Cell-penetrating Peptides Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB06957
Antibacterial Cell-penetrating Peptides Toxicity
Anti-infective peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
AntiBP3 Peptipedia CPPsite3.0
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Cell-penetrating Peptides, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and CPPsite3.0, with an available 3D structural model.
Sequence
CRRWQWRMKKLGC
Physicochemical Analysis
C76H123N27O15S3
ANDEHIFPSTYV
R
1751.16
11.37
5
0
4
+5
0.03
-1.254
30.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
11125
635.29
3
Residue Composition
number
0
A
3
R
0
N
0
D
2
C
0
E
1
Q
1
G
0
H
0
I
1
L
2
K
1
M
0
F
0
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 2 E: 0 Q: 1 G: 1 H: 0 I: 0 L: 1 K: 2 M: 1 F: 0 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
13
C76H123N27O15S3
1751.16
11.37
+5
0.03
-1.254
Evidence Records 3 records
Evidence 1 Activity

Activity

MIC
Antibacterial
20 µg/mL

Target

Escherichia coli

Source & Reference

NA

Other

Active against E. coli (MIC 20 ug/ml) amd S. aureus (MIC 25-50 ug/ml).
Evidence 2 Activity

Activity

MIC
Antibacterial
25-50 µg/mL

Target

Staphylococcus aureus

Source & Reference

NA

Other

Active against E. coli (MIC 20 ug/ml) amd S. aureus (MIC 25-50 ug/ml).
Evidence 3 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Serum stabilities of short tryptophan- and arginine-rich antimicrobial peptide analogs. | PLoS One | 2010