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Peptide record

TPDB06951

Antibacterial Antifungal Hemolysis Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB06951
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
FVRWFSKFLGRIL
Physicochemical Analysis
C84H125N21O15
ANDCEQHMPTY
F
1669.05
12.41
3
0
8
+3
-3.85
0.746
112.31
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
5500
329.53
1
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
2
L
1
K
0
M
3
F
0
P
1
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 2 K: 1 M: 0 F: 3 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
13
C84H125N21O15
1669.05
12.41
+3
-3.85
0.746
Evidence Records 5 records
Evidence 1 Activity

Activity

100% Hemolysis
Toxicity
12 µM
Hemolytic Cytotoxic
100% Hemolysis | 12 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-activity relationship, conformational and biological studies of temporin L analogues. | J Med Chem | 2011
Evidence 2 Activity

Activity

52% Hemolysis
Toxicity
6 µM
Hemolytic Cytotoxic
52% Hemolysis | 6 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-activity relationship, conformational and biological studies of temporin L analogues. | J Med Chem | 2011
Evidence 3 Activity

Activity

20% Hemolysis
Toxicity
3 µM
Hemolytic Cytotoxic
20% Hemolysis | 3 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-activity relationship, conformational and biological studies of temporin L analogues. | J Med Chem | 2011
Evidence 4 Activity

Activity

7% Hemolysis
Toxicity
1.5 µM
Hemolytic Cytotoxic
7% Hemolysis | 1.5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-activity relationship, conformational and biological studies of temporin L analogues. | J Med Chem | 2011
Evidence 5 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis