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Peptide record

TPDB06860

Antibacterial Anticancer Antifungal Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB06860
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia CancerPPD 2.0 SATPdb Antifungipept CAFPdb
standard
No
A 12-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CancerPPD 2.0, and other sources, with an available 3D structural model.
Sequence
LKKLLKKLLKKL
Physicochemical Analysis
C72H140N18O13
ARNDCEQGHIMFPSTWYV
LK
1466.02
11.21
6
0
6
+6
2.58
-0.050
195.00
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
6
L
6
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 6 K: 6 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
12
C72H140N18O13
1466.02
11.21
+6
2.58
-0.050
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>2000 µM
Hemolytic Cytotoxic
50% Hemolysis | >2000 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Disruption of drug-resistant biofilms using de novo designed short ?-helical antimicrobial peptides with idealized facial amphiphilicity. | Acta Biomater | 2017