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Peptide record

TPDB06844

Antibacterial Hemolysis Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB06844
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia PD_Hemolysis
standard
No
A 12-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
KRKIFLRTKILV
Physicochemical Analysis
C72H131N21O14
ANDCEQGHMPSWY
K
1514.96
12.43
5
0
6
+5
1.93
0.183
154.17
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
2
L
3
K
0
M
1
F
0
P
0
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 2 K: 3 M: 0 F: 1 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
12
C72H131N21O14
1514.96
12.43
+5
1.93
0.183
Evidence Records 3 records
Evidence 1 Activity

Activity

12% Hemolysis
Toxicity
8 µM
Hemolytic Cytotoxic
12% Hemolysis | 8 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Effect of tacticity-derived topological constraints in bactericidal peptides. | Biochim Biophys Acta | 2017
Evidence 2 Activity

Activity

11.28-13.12% Hemolysis
Toxicity
16 µM
Hemolytic Cytotoxic
11.28-13.12% Hemolysis | 16 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Bactericidal Potency and Extended Serum Life of Stereo-Chemically Engineered Peptides Against Mycobacterium | Int J Pept Res Ther | 2019
Evidence 3 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis