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Peptide record

TPDB06840

Antibacterial Antifungal standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB06840
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 Peptipedia Antifungipept
standard
No
A 12-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, Peptipedia, and Antifungipept, with an available 3D structural model.
Sequence
IRWRIRVWVRRI
Physicochemical Analysis
C80H133N29O13
ANDCEQGHLKMFPSTY
R
1709.12
13.00
5
0
7
+5
-0.44
-0.200
145.83
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
11000
643.61
0
Residue Composition
number
0
A
5
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
3
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
2
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 3 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 2
Chemical Descriptors
12
C80H133N29O13
1709.12
13.00
+5
-0.44
-0.200
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

IDR-1010 is active against S. aureus and P. aeruginosa (MIC 2.3 and 9 ug/ml). It also demonstrated a potent ability to suppress endotoxin lipopolysaccharide (LPS)-mediated induction of the pro-inflammatory cytokine TNF-alpha in human peripheral blood mononuclear cells (PBMCs) by 94%.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

Antifungipept

Other

IDR-1010 is active against S. aureus and P. aeruginosa (MIC 2.3 and 9 ug/ml). It also demonstrated a potent ability to suppress endotoxin lipopolysaccharide (LPS)-mediated induction of the pro-inflammatory cytokine TNF-alpha in human peripheral blood mononuclear cells (PBMCs) by 94%.