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Peptide record

TPDB06832

W4R8 Antibacterial Cell-penetrating Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB06832
W4R8
Antibacterial Cell-penetrating Peptides
Anti-infective peptides Delivery and barrier-penetrating peptides
AntiBP3 Peptipedia CellPPD-MOD CPPsite3.0 MLCPP 2.0 PerseuCPP
standard
No
A 12-aa standard natural multi-activity (Antibacterial and Cell-penetrating Peptides) peptide sequence curated from AntiBP3, Peptipedia, CellPPD-MOD, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Conjugation with FAM
Sequence
WWWWRRRRRRRR-NH2
Physicochemical Analysis
C92H138N40O13
ANDCEQGHILKMFPSTYV
R
2012.37
13.25
8
0
4
+8
-0.92
-3.300
0.00
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
22000
1093.24
0
Residue Composition
number
0
A
8
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
4
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 8 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 4 Y: 0 V: 0
Chemical Descriptors
12
C92H138N40O13
2012.37
13.25
+8
-0.92
-3.300
Amidation
L
Cationic
Linear
Conjugation with FAM
N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

CHO-K1 cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Synthetic
Fluorophore (FAM)
Plasma membrane or in the Cytosol
Endocytosis
In vitro
CCTHHHHTSCCC
Additional Detail Fields 1 fields
CCTHHHHTSCCC