Back to search

Peptide record

TPDB06822

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB06822
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept ToxinPred 3.0
standard
No
A 12-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
FLPVLAGVLSRA
Physicochemical Analysis
C59H99N15O14
NDCEQHIKMTWY
L
1242.53
11.05
1
0
8
+1
-1.61
1.575
162.50
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
2
A
1
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
3
L
0
K
0
M
1
F
1
P
1
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 3 K: 0 M: 0 F: 1 P: 1 S: 1 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
12
C59H99N15O14
1242.53
11.05
+1
-1.61
1.575
Evidence Records 17 records
Evidence 1 Activity

Activity

MIC
Antibacterial
34.5 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against E. coli (MIC 34.5 ug/ml), S. dysgalactiae (MIC 21.8 ug/ml), S. agalactiae (30.5 ug/ml), S. aureus PTCC 1431 (42.1
Evidence 2 Activity

Activity

MIC
Antibacterial
21.8 µg/mL

Target

S. dysgalactiae

Source & Reference

dbAMP DRAMP

Other

Active against E. coli (MIC 34.5 ug/ml), S. dysgalactiae (MIC 21.8 ug/ml), S. agalactiae (30.5 ug/ml), S. aureus PTCC 1431 (42.1 ug/ml), S. typhimurium PTCC 1428 (
Evidence 3 Activity

Activity

MIC
Antibacterial
31.8 µg/mL

Target

S. typhimurium PTCC 1428

Source & Reference

dbAMP DRAMP

Other

galactiae (MIC 21.8 ug/ml), S. agalactiae (30.5 ug/ml), S. aureus PTCC 1431 (42.1 ug/ml), S. typhimurium PTCC 1428 (MIC 31.8 ug/ml), and K. pneumoniae (MIC 35.1 ug/ml).
Evidence 4 Activity

Activity

MIC
Antibacterial
35.1 µg/mL

Target

Klebsiella pneumoniae

Source & Reference

dbAMP DRAMP

Other

ug/ml), S. aureus PTCC 1431 (42.1 ug/ml), S. typhimurium PTCC 1428 (MIC 31.8 ug/ml), and K. pneumoniae (MIC 35.1 ug/ml).
Evidence 5 Activity

Activity

MIC
Antifungal
34.5 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against E. coli (MIC 34.5 ug/ml), S. dysgalactiae (MIC 21.8 ug/ml), S. agalactiae (30.5 ug/ml), S. aureus PTCC 1431 (42.1
Evidence 6 Activity

Activity

MIC
Antifungal
21.8 µg/mL

Target

S. dysgalactiae

Source & Reference

dbAMP DRAMP Antifungipept

Other

Active against E. coli (MIC 34.5 ug/ml), S. dysgalactiae (MIC 21.8 ug/ml), S. agalactiae (30.5 ug/ml), S. aureus PTCC 1431 (42.1 ug/ml), S. typhimurium PTCC 1428 (
Evidence 7 Activity

Activity

MIC
Antifungal
31.8 µg/mL

Target

S. typhimurium PTCC 1428

Source & Reference

dbAMP DRAMP Antifungipept

Other

galactiae (MIC 21.8 ug/ml), S. agalactiae (30.5 ug/ml), S. aureus PTCC 1431 (42.1 ug/ml), S. typhimurium PTCC 1428 (MIC 31.8 ug/ml), and K. pneumoniae (MIC 35.1 ug/ml).
Evidence 8 Activity

Activity

MIC
Antifungal
35.1 µg/mL

Target

Klebsiella pneumoniae

Source & Reference

dbAMP DRAMP Antifungipept

Other

ug/ml), S. aureus PTCC 1431 (42.1 ug/ml), S. typhimurium PTCC 1428 (MIC 31.8 ug/ml), and K. pneumoniae (MIC 35.1 ug/ml).
Evidence 9 Activity

Activity

MIC
Antiparasitic
34.5 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against E. coli (MIC 34.5 ug/ml), S. dysgalactiae (MIC 21.8 ug/ml), S. agalactiae (30.5 ug/ml), S. aureus PTCC 1431 (42.1
Evidence 10 Activity

Activity

MIC
Antiparasitic
21.8 µg/mL

Target

S. dysgalactiae

Source & Reference

DRAMP

Other

Active against E. coli (MIC 34.5 ug/ml), S. dysgalactiae (MIC 21.8 ug/ml), S. agalactiae (30.5 ug/ml), S. aureus PTCC 1431 (42.1 ug/ml), S. typhimurium PTCC 1428 (
Evidence 11 Activity

Activity

MIC
Antiparasitic
31.8 µg/mL

Target

S. typhimurium PTCC 1428

Source & Reference

DRAMP

Other

galactiae (MIC 21.8 ug/ml), S. agalactiae (30.5 ug/ml), S. aureus PTCC 1431 (42.1 ug/ml), S. typhimurium PTCC 1428 (MIC 31.8 ug/ml), and K. pneumoniae (MIC 35.1 ug/ml).
Evidence 12 Activity

Activity

MIC
Antiparasitic
35.1 µg/mL

Target

Klebsiella pneumoniae

Source & Reference

DRAMP

Other

ug/ml), S. aureus PTCC 1431 (42.1 ug/ml), S. typhimurium PTCC 1428 (MIC 31.8 ug/ml), and K. pneumoniae (MIC 35.1 ug/ml).
Evidence 13 Activity

Activity

MIC
Antiviral
34.5 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Active against E. coli (MIC 34.5 ug/ml), S. dysgalactiae (MIC 21.8 ug/ml), S. agalactiae (30.5 ug/ml), S. aureus PTCC 1431 (42.1
Evidence 14 Activity

Activity

MIC
Antiviral
21.8 µg/mL

Target

S. dysgalactiae

Source & Reference

DRAMP

Other

Active against E. coli (MIC 34.5 ug/ml), S. dysgalactiae (MIC 21.8 ug/ml), S. agalactiae (30.5 ug/ml), S. aureus PTCC 1431 (42.1 ug/ml), S. typhimurium PTCC 1428 (
Evidence 15 Activity

Activity

MIC
Antiviral
31.8 µg/mL

Target

S. typhimurium PTCC 1428

Source & Reference

DRAMP

Other

galactiae (MIC 21.8 ug/ml), S. agalactiae (30.5 ug/ml), S. aureus PTCC 1431 (42.1 ug/ml), S. typhimurium PTCC 1428 (MIC 31.8 ug/ml), and K. pneumoniae (MIC 35.1 ug/ml).
Evidence 16 Activity

Activity

MIC
Antiviral
35.1 µg/mL

Target

Klebsiella pneumoniae

Source & Reference

DRAMP

Other

ug/ml), S. aureus PTCC 1431 (42.1 ug/ml), S. typhimurium PTCC 1428 (MIC 31.8 ug/ml), and K. pneumoniae (MIC 35.1 ug/ml).
Evidence 17 Activity

Activity

1% Hemolysis
Toxicity
60 µg/mL
Hemolytic Cytotoxic
1% Hemolysis | 60 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and characterization of two novel antimicrobial peptides, temporin-Ra and temporin-Rb, from skin secretions of the marsh frog (Rana ridibunda). | J Pept Sci | 2012