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Peptide record

TPDB06821

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB06821
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb ToxinPred 3.0
standard
No
A 12-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GIHDILKYGKPS
Physicochemical Analysis
C61H98N16O17
ARNCEQMFTWV
GIK
1327.55
9.65
3
1
4
+1
2.65
-0.517
97.50
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
112.24
2
Residue Composition
number
0
A
0
R
0
N
1
D
0
C
0
E
0
Q
2
G
1
H
2
I
1
L
2
K
0
M
0
F
1
P
1
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 2 H: 1 I: 2 L: 1 K: 2 M: 0 F: 0 P: 1 S: 1 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
12
C61H98N16O17
1327.55
9.65
+1
2.65
-0.517
Evidence Records 6 records
Evidence 1 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Myxinidin, a novel antimicrobial peptide from the epidermal mucus of hagfish, Myxine glutinosa L. | Mar Biotechnol | 2009
Evidence 2 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Design and membrane-disruption mechanism of charge-enriched AMPs exhibiting cell selectivity, high-salt resistance, and anti-biofilm properties. | Amino Acids | 2016
Evidence 3 Activity

Activity

1% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
1% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-activity relations of myxinidin, an antibacterial peptide derived from the epidermal mucus of hagfish. | Antimicrob Agents Chemother | 2013
Evidence 4 Activity

Activity

5% Hemolysis
Toxicity
200 µM
Hemolytic Cytotoxic
5% Hemolysis | 200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-activity relations of myxinidin, an antibacterial peptide derived from the epidermal mucus of hagfish. | Antimicrob Agents Chemother | 2013
Evidence 5 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Vero cells

Target

Vero cells

Source & Reference

NA
DBAASP
Structure-activity relations of myxinidin, an antibacterial peptide derived from the epidermal mucus of hagfish. | Antimicrob Agents Chemother | 2013
Evidence 6 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref.19330556] Non-hemolytic activity against rabbit red blood cells at concentrations 50-fold higher than its antimicrobial activity.

Target

erythrocytes

Source & Reference

NA
DRAMP
Mar Biotechnol (NY). 2009 Nov-Dec 11(6):748-757.