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Peptide record

TPDB06819

Antibacterial Anticancer Antifungal Antiparasitic standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB06819
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 Peptipedia AFP-GFuse Antifungipept CAFPdb DRAMP pep-lab dbAMP dbAMP 3.0 i2APP
standard
No
A 12-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, AFP-GFuse, and other sources, with an available 3D structural model.
Sequence
HPLKQYWWRPSI
Physicochemical Analysis
C79H111N21O16
ANDCEGMFTV
PW
1610.88
10.42
3
0
5
+2
-1.14
-1.158
65.00
Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour
12490
775.35
3
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
1
Q
0
G
1
H
1
I
1
L
1
K
0
M
0
F
2
P
1
S
0
T
2
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 1 I: 1 L: 1 K: 1 M: 0 F: 0 P: 2 S: 1 T: 0 W: 2 Y: 1 V: 0
Chemical Descriptors
12
C79H111N21O16
1610.88
10.42
+2
-1.14
-1.158
Evidence Records 12 records
Evidence 1 Activity

Activity

MIC
Antibacterial
12.5-25 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
DRAMP antibacterial activity supported by MIC records against bacterial target organisms. dbAMP classified as Antibacterial under the Anti-bacterial function class.
tivity against E. acervulina and E. tenella sporozoites (parasites). Active against fungi C. albicans (MIC 12.5-25 ug/ml) and A. nidulans (MIC 25-50 ug/ml). inactive against E.coli (MIC>125 uM), S.aureus (MIC>12
Evidence 2 Activity

Activity

MIC
Antibacterial
25-50 µg/mL

Target

A. nidulans

Source & Reference

dbAMP DRAMP

Other

tenella sporozoites (parasites). Active against fungi C. albicans (MIC 12.5-25 ug/ml) and A. nidulans (MIC 25-50 ug/ml). inactive against E.coli (MIC>125 uM), S.aureus (MIC>125 uM), M.luteus (no effect at 200
Evidence 3 Activity

Activity

MIC
Antibacterial
>125 µM

Target

E.coli

Source & Reference

dbAMP DRAMP

Other

fungi C. albicans (MIC 12.5-25 ug/ml) and A. nidulans (MIC 25-50 ug/ml). inactive against E.coli (MIC>125 uM), S.aureus (MIC>125 uM), M.luteus (no effect at 200 ug/ml) (see ref for Pac-525).
Evidence 4 Activity

Activity

MIC
Antibacterial
>125 µM

Target

S.aureus

Source & Reference

dbAMP DRAMP

Other

C 12.5-25 ug/ml) and A. nidulans (MIC 25-50 ug/ml). inactive against E.coli (MIC>125 uM), S.aureus (MIC>125 uM), M.luteus (no effect at 200 ug/ml) (see ref for Pac-525).
Evidence 5 Activity

Activity

MIC
Antifungal
12.5-25 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
DRAMP antifungal activity supported by activity records against fungal target organisms. dbAMP classified under the Anti-fungal function class.
tivity against E. acervulina and E. tenella sporozoites (parasites). Active against fungi C. albicans (MIC 12.5-25 ug/ml) and A. nidulans (MIC 25-50 ug/ml). inactive against E.coli (MIC>125 uM), S.aureus (MIC>12
Evidence 6 Activity

Activity

MIC
Antifungal
25-50 µg/mL

Target

A. nidulans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

tenella sporozoites (parasites). Active against fungi C. albicans (MIC 12.5-25 ug/ml) and A. nidulans (MIC 25-50 ug/ml). inactive against E.coli (MIC>125 uM), S.aureus (MIC>125 uM), M.luteus (no effect at 200
Evidence 7 Activity

Activity

MIC
Antifungal
>125 µM

Target

E.coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

fungi C. albicans (MIC 12.5-25 ug/ml) and A. nidulans (MIC 25-50 ug/ml). inactive against E.coli (MIC>125 uM), S.aureus (MIC>125 uM), M.luteus (no effect at 200 ug/ml) (see ref for Pac-525).
Evidence 8 Activity

Activity

MIC
Antifungal
>125 µM

Target

S.aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

C 12.5-25 ug/ml) and A. nidulans (MIC 25-50 ug/ml). inactive against E.coli (MIC>125 uM), S.aureus (MIC>125 uM), M.luteus (no effect at 200 ug/ml) (see ref for Pac-525).
Evidence 9 Activity

Activity

MIC
Antiparasitic
12.5-25 µg/mL

Target

Candida albicans

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets. dbAMP 3.0 classified under the Anti-parasitic function class.
tivity against E. acervulina and E. tenella sporozoites (parasites). Active against fungi C. albicans (MIC 12.5-25 ug/ml) and A. nidulans (MIC 25-50 ug/ml). inactive against E.coli (MIC>125 uM), S.aureus (MIC>12
Evidence 10 Activity

Activity

MIC
Antiparasitic
25-50 µg/mL

Target

A. nidulans

Source & Reference

dbAMP 3.0 DRAMP

Other

tenella sporozoites (parasites). Active against fungi C. albicans (MIC 12.5-25 ug/ml) and A. nidulans (MIC 25-50 ug/ml). inactive against E.coli (MIC>125 uM), S.aureus (MIC>125 uM), M.luteus (no effect at 200
Evidence 11 Activity

Activity

MIC
Antiparasitic
>125 µM

Target

E.coli

Source & Reference

dbAMP 3.0 DRAMP

Other

fungi C. albicans (MIC 12.5-25 ug/ml) and A. nidulans (MIC 25-50 ug/ml). inactive against E.coli (MIC>125 uM), S.aureus (MIC>125 uM), M.luteus (no effect at 200 ug/ml) (see ref for Pac-525).
Evidence 12 Activity

Activity

MIC
Antiparasitic
>125 µM

Target

S.aureus

Source & Reference

dbAMP 3.0 DRAMP

Other

C 12.5-25 ug/ml) and A. nidulans (MIC 25-50 ug/ml). inactive against E.coli (MIC>125 uM), S.aureus (MIC>125 uM), M.luteus (no effect at 200 ug/ml) (see ref for Pac-525).