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Peptide record

TPDB06803

Antibacterial Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB06803
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia
standard
No
A 12-aa standard-residue multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
LLAAHLLAIGRR
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C59H106N20O13
NDCEQKMFPSTWYV
L
1303.62
12.40
3
0
8
+2
0.29
1.042
187.50
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
3
A
2
R
0
N
0
D
0
C
0
E
0
Q
1
G
1
H
1
I
4
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 1 L: 4 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
12 reviewed residue count
C59H106N20O13 sequence-only estimate (linear, free termini)
1303.62 sequence-only estimate (linear, free termini)
12.40 sequence-only estimate (linear, free termini)
+2 sequence-only estimate (linear, free termini)
0.29 sequence-only estimate (linear, free termini)
1.042 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Synthesis and characterization of bactericidal oligopeptides designed on the basis of an insect anti-bacterial peptide. | Biochem J | 1999