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Peptide record

TPDB06801

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB06801
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 12-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
ILPILSLIGGLL
Physicochemical Analysis
C60H108N12O14
ARNDCEQHKMFTWYV
L
1221.59
6.02
0
0
8
-0
-3.13
2.442
260.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
3
I
5
L
0
K
0
M
0
F
1
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 3 L: 5 K: 0 M: 0 F: 0 P: 1 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
12
C60H108N12O14
1221.59
6.02
-0
-3.13
2.442
Evidence Records 4 records
Evidence 1 Activity

Activity

Hemolysis
Human erythrocytes: LD50=112 µM

Target

Human erythrocytes

Source & Reference

Hemolytik PD_Hemolysis
DRAMP4
Zoolog Sci. 2009 Mar 26(3):220-6.

Other

Source Activity Label Source Definition
Hemolysis
Hemolytik experimentally validated hemolytic peptide annotation.
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
180 µM
Hemolytic Cytotoxic
50% Hemolysis | 180 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Characterization of antimicrobial peptides isolated from the skin of the Chinese frog, Rana dybowskii. | Comp Biochem Physiol B Biochem Mol Biol | 2009
Evidence 3 Activity

Activity

LD50
Toxicity
112 µM
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes: LD50=112 µM | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Zoolog Sci. 2009 Mar 26(3):220-6.
Evidence 4 Hemolysis

Activity

Human erythrocytes: LD50=112 µM
Hemolysis

Target

Human erythrocytes

Source & Reference

HemoPI PD_Hemolysis
Zoolog Sci. 2009 Mar 26(3):220-6.
DRAMP4
PD_Hemolysis