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Peptide record

TPDB06800

Antibacterial Anticancer Antifungal Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB06800
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia SATPdb dbACP AFP-GFuse Antifungipept CAFPdb dbAMP ToxinPred 3.0
standard
No
A 12-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, SATPdb, and other sources, with an available 3D structural model.
Sequence
FLPLKKLRFGLL
Physicochemical Analysis
C73H121N17O13
ANDCEQHIMSTWYV
L
1444.87
11.64
3
0
7
+3
-1.81
0.858
162.50
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
5
L
2
K
0
M
2
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 5 K: 2 M: 0 F: 2 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
12
C73H121N17O13
1444.87
11.64
+3
-1.81
0.858
Evidence Records 8 records
Evidence 1 Activity

Activity

MIC
Antibacterial
12.5 µM

Target

Pseudomonas aeruginosa

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against E. coli, P. aeruginosa (MIC 12.5 uM), S. aureus, B. cereus, S. lactis (MIC 3.13 uM), C. albicans (MIC 6.25 uM), and cancer cel
Evidence 2 Activity

Activity

MIC
Antibacterial
3.13 µM

Target

S. lactis

Source & Reference

dbAMP

Other

Active against E. coli, P. aeruginosa (MIC 12.5 uM), S. aureus, B. cereus, S. lactis (MIC 3.13 uM), C. albicans (MIC 6.25 uM), and cancer cells MCF 7 cells and Hela cells (IC50 ~12 uM).
Evidence 3 Activity

Activity

MIC
Antibacterial
6.25 µM

Target

Candida albicans

Source & Reference

dbAMP

Other

inst E. coli, P. aeruginosa (MIC 12.5 uM), S. aureus, B. cereus, S. lactis (MIC 3.13 uM), C. albicans (MIC 6.25 uM), and cancer cells MCF 7 cells and Hela cells (IC50 ~12 uM).
Evidence 4 Activity

Activity

MIC
Antifungal
12.5 µM

Target

Pseudomonas aeruginosa

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against E. coli, P. aeruginosa (MIC 12.5 uM), S. aureus, B. cereus, S. lactis (MIC 3.13 uM), C. albicans (MIC 6.25 uM), and cancer cel
Evidence 5 Activity

Activity

MIC
Antifungal
3.13 µM

Target

S. lactis

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against E. coli, P. aeruginosa (MIC 12.5 uM), S. aureus, B. cereus, S. lactis (MIC 3.13 uM), C. albicans (MIC 6.25 uM), and cancer cells MCF 7 cells and Hela cells (IC50 ~12 uM).
Evidence 6 Activity

Activity

MIC
Antifungal
6.25 µM

Target

Candida albicans

Source & Reference

dbAMP CAFPdb Antifungipept

Other

inst E. coli, P. aeruginosa (MIC 12.5 uM), S. aureus, B. cereus, S. lactis (MIC 3.13 uM), C. albicans (MIC 6.25 uM), and cancer cells MCF 7 cells and Hela cells (IC50 ~12 uM).
Evidence 7 Activity

Activity

50% Hemolysis
Toxicity
136.3±5.6 µM
Hemolytic Cytotoxic
50% Hemolysis | 136.3±5.6 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Purification, molecular cloning, and antimicrobial activity of peptides from the skin secretion of the black-spotted frog, Rana nigromaculata. | World J Microbiol Biotechnol | 2013
Evidence 8 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
World J Microbiol Biotechnol. 2013 Oct 29(10):1941-9.