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Peptide record

TPDB06797

Antibacterial Antiparasitic Cell-penetrating Peptides Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB06797
Antibacterial Antiparasitic Cell-penetrating Peptides Toxicity
Anti-infective peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
AntiBP3 Peptipedia i2APP CPPsite3.0
standard
No
A 12-aa standard natural multi-activity (Antibacterial, Antiparasitic, Cell-penetrating Peptides, and other sources) peptide sequence curated from AntiBP3, Peptipedia, i2APP, and other sources, with an available 3D structural model.
Sequence
VRLIVAVRIWRR
Physicochemical Analysis
C71H125N25O13
NDCEQGHKMFPSTY
R
1536.93
12.88
4
0
8
+4
0.25
0.692
178.33
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
5500
357.86
0
Residue Composition
number
1
A
4
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
1
L
0
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
3
V
Amino Acid Distribution
A: 1 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 1 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 3
Chemical Descriptors
12
C71H125N25O13
1536.93
12.88
+4
0.25
0.692
Evidence Records 2 records
Evidence 1 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Human monocytes

Target

Human monocytes

Source & Reference

NA
DBAASP
Ability of innate defence regulator peptides IDR-1002, IDR-HH2 and IDR-1018 to protect against Mycobacterium tuberculosis infections in animal models. | PLoS One | 2013
Evidence 2 Activity

Activity

<15% Cytotoxicity
Toxicity
40 µM
Cytotoxic
<15% Cytotoxicity | 40 | µM | target cell: Human PBMC

Target

Human PBMC

Source & Reference

NA
DBAASP
Computer-aided Discovery of Peptides that Specifically Attack Bacterial Biofilms. | Sci Rep | 2018