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Peptide record

TPDB06771

Antibacterial Hemolysis Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB06771
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia PD_Hemolysis
standard
No
A 12-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
RLCPRVRIRVCR
Physicochemical Analysis
C63H119N27O13S2
ANDEQGHKMFSTWY
R
1526.93
12.23
5
0
4
+5
3.29
-0.200
113.33
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
125
8.19
2
Residue Composition
number
0
A
5
R
0
N
0
D
2
C
0
E
0
Q
0
G
0
H
1
I
1
L
0
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 1 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
12
C63H119N27O13S2
1526.93
12.23
+5
3.29
-0.200
Evidence Records 2 records
Evidence 1 Activity

Activity

MHC
Toxicity
>32 µg/mL
Hemolytic Cytotoxic
MHC | >32 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Improved derivatives of bactenecin, a cyclic dodecameric antimicrobial cationic peptide. | Antimicrob Agents Chemother | 1999
Evidence 2 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis