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Peptide record

TPDB06739

Antibacterial Hemolysis Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB06739
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 12-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
KLFKRHLKWKII
Physicochemical Analysis
C80H132N22O13
ANDCEQGMPSTYV
K
1610.07
11.80
6
0
6
+5
1.01
-0.400
130.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
341.60
0
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
1
H
2
I
2
L
4
K
0
M
1
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 2 L: 2 K: 4 M: 0 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
12
C80H132N22O13
1610.07
11.80
+5
1.01
-0.400
Evidence Records 3 records
Evidence 1 Activity

Activity

15% Hemolysis
Toxicity
3 µM
Hemolytic Cytotoxic
15% Hemolysis | 3 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Promotion of peptide antimicrobial activity by fatty acid conjugation. | Bioconjug Chem | 2004
Evidence 2 Activity

Activity

90% Hemolysis
Toxicity
18 µM
Hemolytic Cytotoxic
90% Hemolysis | 18 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Promotion of peptide antimicrobial activity by fatty acid conjugation. | Bioconjug Chem | 2004
Evidence 3 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis