Back to search

Peptide record

TPDB06704

Antibacterial Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB06704
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia
standard
No
A 12-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
WKSDVRRWRSRY
Physicochemical Analysis
C76H115N27O18
ANCEQGHILMFPT
R
1694.92
11.95
5
1
4
+4
1.15
-2.158
24.17
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
12490
736.91
3
Residue Composition
number
0
A
4
R
0
N
1
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
1
K
0
M
0
F
0
P
2
S
0
T
2
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 1 M: 0 F: 0 P: 0 S: 2 T: 0 W: 2 Y: 1 V: 1
Chemical Descriptors
12
C76H115N27O18
1694.92
11.95
+4
1.15
-2.158
Evidence Records 2 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
0% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-activity relationship of potent antimicrobial peptide analogs of Ixosin-B amide. | Bioorg Med Chem Lett | 2013
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
0.9 %
Hemolytic
Hemolytic_activity: [Ref.23570790]0.3±0.9% hemolysis at 100µM against human red blood cells.

Target

erythrocytes

Source & Reference

NA
DRAMP
Bioorg Med Chem Lett. 2013 May 15 23(10):2929-32.