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Peptide record

TPDB06700

Antibacterial Antifungal Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB06700
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP
standard
No
A 12-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, AFP-GFuse, and other sources, with an available 3D structural model.
Sequence
RMKLNAKKLSFC
Physicochemical Analysis
C63H111N19O15S2
DEQGHIPTWYV
K
1438.81
10.83
4
0
5
+4
1.44
-0.325
73.33
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
3
Residue Composition
number
1
A
1
R
1
N
0
D
1
C
0
E
0
Q
0
G
0
H
0
I
2
L
3
K
1
M
1
F
0
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 1 D: 0 C: 1 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 2 K: 3 M: 1 F: 1 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
12
C63H111N19O15S2
1438.81
10.83
+4
1.44
-0.325
Evidence Records 3 records
Evidence 1 Activity

Activity

MIC
Antibacterial
16 µg/mL

Target

Candida albicans ATCC 14053

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against C. albicans ATCC 14053 (MIC 16 ug/ml). Note that the mature sequence may differ from the synthetic peptide used here. Updated 7
Evidence 2 Activity

Activity

MIC
Antifungal
16 µg/mL

Target

Candida albicans ATCC 14053

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against C. albicans ATCC 14053 (MIC 16 ug/ml). Note that the mature sequence may differ from the synthetic peptide used here. Updated 7
Evidence 3 Activity

Activity

0% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 200 | µg/mL | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
De Novo Transcriptome Analysis and Detection of Antimicrobial Peptides of the American Cockroach Periplaneta americana (Linnaeus). | PLoS One | 2016