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Peptide record

TPDB06657

Antibacterial standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB06657
Antibacterial
Anti-infective peptides
AntiBP3 Peptipedia
standard
No
A 12-aa standard natural antibacterial peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
AKKFGKAFVKIL
Physicochemical Analysis
C67H112N16O13
RNDCEQHMPSTWY
K
1349.73
11.00
4
0
7
+4
0.57
0.475
105.83
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
1
L
4
K
0
M
2
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 1 K: 4 M: 0 F: 2 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
12
C67H112N16O13
1349.73
11.00
+4
0.57
0.475
Evidence Records 2 records
Evidence 1 Activity

Activity

MIC
Antibacterial
128 µg/mL

Target

S.epidermidis ATCC 35984

Source & Reference

NA

Other

active against S.aureus ATCC 25923 or ATCC 33591 MRSA (MIC 128-256 ug/ml, MRSA-inactive), S.epidermidis ATCC 35984 (MIC 128 ug/ml), and P. aeruginosa ATCC 27853 (MIC 32-64 ug/ml).
Evidence 2 Activity

Activity

MIC
Antibacterial
32-64 µg/mL

Target

Pseudomonas aeruginosa ATCC 27853

Source & Reference

NA

Other

91 MRSA (MIC 128-256 ug/ml, MRSA-inactive), S.epidermidis ATCC 35984 (MIC 128 ug/ml), and P. aeruginosa ATCC 27853 (MIC 32-64 ug/ml).