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Peptide record

TPDB06644

Antibacterial Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB06644
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 12-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
FKVTWKTKWWKG
Physicochemical Analysis
C81H115N19O15
ARNDCEQHILMPSY
K
1594.92
11.00
4
0
5
+4
-2.36
-1.092
24.17
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
16500
1034.53
2
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
0
L
4
K
0
M
1
F
0
P
0
S
2
T
3
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 4 M: 0 F: 1 P: 0 S: 0 T: 2 W: 3 Y: 0 V: 1
Chemical Descriptors
12
C81H115N19O15
1594.92
11.00
+4
-2.36
-1.092
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>600 µM
Hemolytic Cytotoxic
50% Hemolysis | >600 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Mechanism of action of puroindoline derived tryptophan-rich antimicrobial peptides. | Biochim Biophys Acta | 2013