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Peptide record

TPDB06638

Antibacterial standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB06638
Antibacterial
Anti-infective peptides
AntiBP3 Peptipedia
standard
No
A 12-aa standard natural antibacterial peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
KFGKAFVKILKK
Physicochemical Analysis
C70H119N17O13
RNDCEQHMPSTWY
K
1406.82
11.12
5
0
6
+5
1.73
-0.000
97.50
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
1
L
5
K
0
M
2
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 1 K: 5 M: 0 F: 2 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
12
C70H119N17O13
1406.82
11.12
+5
1.73
-0.000
Evidence Records 2 records
Evidence 1 Activity

Activity

MIC
Antibacterial
64-128 µg/mL

Target

S.epidermidis ATCC 35984

Source & Reference

NA

Other

active against S.aureus ATCC 25923 or ATCC 33591 MRSA (MIC 256-512 ug/ml, MRSA-inactive), S.epidermidis ATCC 35984 (MIC 64-128 ug/ml), and P. aeruginosa ATCC 27853 (MIC 16-32 ug/ml).
Evidence 2 Activity

Activity

MIC
Antibacterial
16-32 µg/mL

Target

Pseudomonas aeruginosa ATCC 27853

Source & Reference

NA

Other

MRSA (MIC 256-512 ug/ml, MRSA-inactive), S.epidermidis ATCC 35984 (MIC 64-128 ug/ml), and P. aeruginosa ATCC 27853 (MIC 16-32 ug/ml).