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Peptide record

TPDB06621

Antibacterial Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB06621
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 DRAMP pep-lab Peptipedia
standard
No
A 12-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, DRAMP, pep-lab, and other sources, with an available 3D structural model.
Sequence
GLPGPLGPAGPK
Physicochemical Analysis
C49H81N13O13
RNDCEQHIMFSTWYV
GP
1060.26
10.10
1
0
3
+1
1.54
-0.208
73.33
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
4
G
0
H
0
I
2
L
1
K
0
M
0
F
4
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 4 H: 0 I: 0 L: 2 K: 1 M: 0 F: 0 P: 4 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
12
C49H81N13O13
1060.26
10.10
+1
1.54
-0.208
Evidence Records 3 records
Evidence 1 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Collagencin, an antibacterial peptide from fish collagen: Activity, structure and interaction dynamics with membrane. | Biochem Biophys Res Commun | 2016
Evidence 2 Activity

Activity

25% Hemolysis
Toxicity
940 µM
Hemolytic Cytotoxic
25% Hemolysis | 940 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Collagencin, an antibacterial peptide from fish collagen: Activity, structure and interaction dynamics with membrane. | Biochem Biophys Res Commun | 2016
Evidence 3 Activity

Activity

% Hemolysis
Toxicity
25 %
Hemolytic
Hemolytic_activity: [Ref.27038545]non-toxic to horse erythrocytes up to 470 µM 25% hemolysis against horse erythrocytes at 940 µM.

Target

erythrocytes

Source & Reference

NA
DRAMP
Biochem Biophys Res Commun. 2016 Apr 29 473(2):642-7.