Peptide record

TPDB06619

Antibacterial Antifungal Hemolysis Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB06619
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP PD_Hemolysis
standard
No
A 12-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
GKWWSLLKHILK
Physicochemical Analysis
C75H117N19O14
ARNDCEQMFPTYV
LK
1508.87
10.84
4
0
6
+3
-1.62
-0.167
130.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
11000
729.02
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
1
H
1
I
3
L
3
K
0
M
0
F
0
P
1
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 1 L: 3 K: 3 M: 0 F: 0 P: 0 S: 1 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
12
C75H117N19O14
1508.87
10.84
+3
-1.62
-0.167
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
33 µM
Hemolytic Cytotoxic
50% Hemolysis | 33 | µM | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
Novel antimicrobial peptides from the venom of the eusocial bee Halictus sexcinctus (Hymenoptera: Halictidae) and their analogs. | Amino Acids | 2010
Evidence 2 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis