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Peptide record

TPDB06605

Antibacterial Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB06605
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 12-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GIHDILKYGKRS
Physicochemical Analysis
C62H103N19O17
ANCEQMFPTWV
GIK
1386.62
10.19
4
1
4
+2
3.01
-0.758
97.50
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
107.46
2
Residue Composition
number
0
A
1
R
0
N
1
D
0
C
0
E
0
Q
2
G
1
H
2
I
1
L
2
K
0
M
0
F
0
P
1
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 2 H: 1 I: 2 L: 1 K: 2 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
12
C62H103N19O17
1386.62
10.19
+2
3.01
-0.758
Evidence Records 9 records
Evidence 1 Activity

Activity

MIC
Antibacterial
10 µM

Target

Escherichia coli ATCC 11219

Source & Reference

NA

Other

active against E. coli ATCC 11219 (MIC 10 uM), P. aeruginosa ATCC 13388 (MIC 20 uM), S. enterica serovar Typhimurium ATCC 14028 (MIC 20
Evidence 2 Activity

Activity

MIC
Antibacterial
20 µM

Target

Pseudomonas aeruginosa ATCC 13388

Source & Reference

NA

Other

active against E. coli ATCC 11219 (MIC 10 uM), P. aeruginosa ATCC 13388 (MIC 20 uM), S. enterica serovar Typhimurium ATCC 14028 (MIC 20 uM), K. pneumoniae ATCC 10031 (MIC 10
Evidence 3 Activity

Activity

MIC
Antibacterial
20 µM

Target

S. enterica serovar Typhimurium ATCC 14028

Source & Reference

NA

Other

active against E. coli ATCC 11219 (MIC 10 uM), P. aeruginosa ATCC 13388 (MIC 20 uM), S. enterica serovar Typhimurium ATCC 14028 (MIC 20 uM), K. pneumoniae ATCC 10031 (MIC 10 uM), S. aureus ATCC 6538 (MIC 10 uM).
Evidence 4 Activity

Activity

MIC
Antibacterial
10 µM

Target

Klebsiella pneumoniae ATCC 10031

Source & Reference

NA

Other

eruginosa ATCC 13388 (MIC 20 uM), S. enterica serovar Typhimurium ATCC 14028 (MIC 20 uM), K. pneumoniae ATCC 10031 (MIC 10 uM), S. aureus ATCC 6538 (MIC 10 uM).
Evidence 5 Activity

Activity

MIC
Antibacterial
10 µM

Target

Staphylococcus aureus ATCC 6538

Source & Reference

NA

Other

nterica serovar Typhimurium ATCC 14028 (MIC 20 uM), K. pneumoniae ATCC 10031 (MIC 10 uM), S. aureus ATCC 6538 (MIC 10 uM).
Evidence 6 Activity

Activity

6% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
6% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-activity relations of myxinidin, an antibacterial peptide derived from the epidermal mucus of hagfish. | Antimicrob Agents Chemother | 2013
Evidence 7 Activity

Activity

8% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
8% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-activity relations of myxinidin, an antibacterial peptide derived from the epidermal mucus of hagfish. | Antimicrob Agents Chemother | 2013
Evidence 8 Activity

Activity

12% Hemolysis
Toxicity
200 µM
Hemolytic Cytotoxic
12% Hemolysis | 200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-activity relations of myxinidin, an antibacterial peptide derived from the epidermal mucus of hagfish. | Antimicrob Agents Chemother | 2013
Evidence 9 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Vero cells

Target

Vero cells

Source & Reference

NA
DBAASP
Structure-activity relations of myxinidin, an antibacterial peptide derived from the epidermal mucus of hagfish. | Antimicrob Agents Chemother | 2013