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Peptide record

TPDB06554

Antibacterial Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB06554
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 12-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
RVCSWIPLPICH
Physicochemical Analysis
C65H102N18O14S2
ANDEQGKMFTY
CIP
1423.76
8.30
2
0
5
+1
-0.64
0.783
121.67
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5625
395.08
3
Residue Composition
number
0
A
1
R
0
N
0
D
2
C
0
E
0
Q
0
G
1
H
2
I
1
L
0
K
0
M
0
F
2
P
1
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 0 H: 1 I: 2 L: 1 K: 0 M: 0 F: 0 P: 2 S: 1 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
12
C65H102N18O14S2
1423.76
8.30
+1
-0.64
0.783
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
265±16 µM
Hemolytic Cytotoxic
50% Hemolysis | 265±16 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Insulin-releasing and cytotoxic properties of the frog skin peptide, tigerinin-1R: a structure-activity study. | Peptides | 2014