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Peptide record

TPDB06519

Antibacterial Antifungal Hemolysis Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB06519
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP PD_Hemolysis
standard
No
A 12-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
LRFLKKILKHLF
Physicochemical Analysis
C78H130N20O13
ANDCEQGMPSTWYV
L
1556.02
11.73
5
0
7
+4
-0.07
0.492
162.50
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
1
H
1
I
4
L
3
K
0
M
2
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 1 L: 4 K: 3 M: 0 F: 2 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
12
C78H130N20O13
1556.02
11.73
+4
-0.07
0.492
Evidence Records 3 records
Evidence 1 Activity

Activity

25% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
25% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
De-novo design of antimicrobial peptides for plant protection. | PLoS One | 2013
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
30 µM
Hemolytic Cytotoxic
50% Hemolysis | 30 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A de novo-designed antimicrobial peptide with activity against multiresistant Staphylococcus aureus acting on RsbW kinase. | FASEB J | 2013
Evidence 3 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis