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Peptide record

TPDB06489

Antibacterial Antifungal Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB06489
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 12-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
LLKKLLKKLLKL
Physicochemical Analysis
C72H139N17O13
ARNDCEQGHIMFPSTWYV
L
1451.00
11.12
5
0
7
+5
1.03
0.592
227.50
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
7
L
5
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 7 K: 5 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
12
C72H139N17O13
1451.00
11.12
+5
1.03
0.592
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>500 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >500 | µg/mL | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
Rationally designed ?-helical broad-spectrum antimicrobial peptides with idealized facial amphiphilicity. | Macromol Rapid Commun | 2013