Back to search

Peptide record

TPDB06466

Antibacterial Antifungal Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB06466
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb
standard
No
A 12-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
RLKKIGKVLKWI
Physicochemical Analysis
C72H128N20O13
ANDCEQHMFPSTY
K
1481.93
11.80
5
0
6
+5
1.26
-0.050
154.17
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5500
371.14
0
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
2
I
2
L
4
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 2 L: 2 K: 4 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
12
C72H128N20O13
1481.93
11.80
+5
1.26
-0.050
Evidence Records 2 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
>128 µM
Hemolytic Cytotoxic
5% Hemolysis | >128 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Evidence 2 Activity

Activity

MHC
Toxicity
128 µM
Hemolytic
Hemolytic_activity: [Ref.27251456] Non-hemolysis upto 128 µM, MHC>128 µM against human red blood cells.

Target

erythrocytes

Source & Reference

NA
DRAMP
Sci Rep. 2016 Jun 2 6:27258.