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Peptide record

TPDB06455

Antibacterial Anticancer Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB06455
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 12-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
ACFLTRLGTYVC
Physicochemical Analysis
C60H95N15O16S2
NDEQHIKMPSW
CLT
1346.63
8.28
1
0
6
+1
-2.67
1.150
97.50
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
1615
119.93
5
Residue Composition
number
1
A
1
R
0
N
0
D
2
C
0
E
0
Q
1
G
0
H
0
I
2
L
0
K
0
M
1
F
0
P
0
S
2
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 2 K: 0 M: 0 F: 1 P: 0 S: 0 T: 2 W: 0 Y: 1 V: 1
Chemical Descriptors
12
C60H95N15O16S2
1346.63
8.28
+1
-2.67
1.150
Evidence Records 1 records
Evidence 1 Activity

Activity

3.8% Hemolysis
Toxicity
256 µg/mL
Hemolytic Cytotoxic
3.8% Hemolysis | 256 | µg/mL | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Host-defense peptides AC12, DK16 and RC11 with immunomodulatory activity isolated from Hypsiboas raniceps skin secretion. | Peptides | 2019