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Peptide record

TPDB06447

Antibacterial Antifungal Hemolysis Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB06447
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 12-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
ILGIITSLLKSL
Physicochemical Analysis
C60H111N13O16
ARNDCEQHMFPWYV
L
1270.62
10.10
1
0
7
+1
-1.77
1.842
227.50
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
3
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
3
I
4
L
1
K
0
M
0
F
0
P
2
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 3 L: 4 K: 1 M: 0 F: 0 P: 0 S: 2 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
12
C60H111N13O16
1270.62
10.10
+1
-1.77
1.842
Evidence Records 4 records
Evidence 1 Activity

Activity

% Hemolysis
Hemolysis
84 %
[Ref.18695936]84% hemolytic activity at 50 µM against sheep blood cells.

Source & Reference

Hemolytik PD_Hemolysis
DRAMP4
Toxicon. 2010 Apr 1 55(4):711-718.##Amino Acids. 2009 Jul 37(2):389-394.

Other

Source Activity Label Source Definition
Hemolysis
Hemolytik experimentally validated hemolytic peptide annotation.
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
31 µM
Hemolytic Cytotoxic
50% Hemolysis | 31 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Venom peptides from solitary hunting wasps induce feeding disorder in lepidopteran larvae. | Peptides | 2011
Evidence 3 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref.18695936]84% hemolytic activity at 50 µM against sheep blood cells.

Target

erythrocytes

Source & Reference

NA
DRAMP
Toxicon. 2010 Apr 1 55(4):711-718.##Amino Acids. 2009 Jul 37(2):389-394.
Evidence 4 Hemolysis

Activity

84 %
% Hemolysis
[Ref.18695936]84% hemolytic activity at 50 µM against sheep blood cells.
Hemolysis

Source & Reference

HemoPI PD_Hemolysis
Toxicon. 2010 Apr 1 55(4):711-718.##Amino Acids. 2009 Jul 37(2):389-394.
DRAMP4
PD_Hemolysis