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Peptide record

TPDB06446

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB06446
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb
standard
No
A 12-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
AERVGAGAPVYL
Physicochemical Analysis
C54H87N15O16
NDCQHIKMFSTW
A
1202.38
6.90
1
1
7
-0
1.43
0.492
105.83
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
1490
123.92
1
Residue Composition
number
3
A
1
R
0
N
0
D
0
C
1
E
0
Q
2
G
0
H
0
I
1
L
0
K
0
M
0
F
1
P
0
S
0
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 3 R: 1 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 2 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 1 V: 2
Chemical Descriptors
12
C54H87N15O16
1202.38
6.90
-0
1.43
0.492
Evidence Records 1 records
Evidence 1 Activity

Activity

1% Hemolysis
Toxicity
>100 µM
Hemolytic Cytotoxic
1% Hemolysis | >100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Characterisation and evaluation of synthetic antimicrobial peptides against Bacillus globigii, Bacillus anthracis and Burkholderia thailandensis. | Int J Antimicrob Agents | 2010