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Peptide record

TPDB06419

Antibacterial Anticancer Antifungal Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB06419
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 11-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
AARIILRDRFR
Physicochemical Analysis
C61H107N23O14
NCEQGHKMPSTWYV
R
1386.67
12.40
4
1
6
+3
1.82
-0.209
124.55
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
2
A
4
R
0
N
1
D
0
C
0
E
0
Q
0
G
0
H
2
I
1
L
0
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 4 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 1 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
11
C61H107N23O14
1386.67
12.40
+3
1.82
-0.209
Evidence Records 1 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
>128 µM
Hemolytic Cytotoxic
10% Hemolysis | >128 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. Pubmed | J Med Chem | 2019