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Peptide record

TPDB06414

Antibacterial Anticancer Antifungal Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB06414
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP
standard
No
A 11-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
RKIKRYLRRMI
Physicochemical Analysis
C68H125N25O13S1
ANDCEQGHFPSTWV
R
1532.96
12.41
6
0
5
+6
2.87
-1.127
106.36
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1490
97.20
1
Residue Composition
number
0
A
4
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
1
L
2
K
1
M
0
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 1 K: 2 M: 1 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
11
C68H125N25O13S1
1532.96
12.41
+6
2.87
-1.127
Evidence Records 3 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
1660 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | 1660 | µg/mL | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial activity and secondary structure of a novel peptide derived from ovalbumin | J Pept Sci | 2020
Evidence 2 Activity

Activity

<5% Hemolysis
Toxicity
800 µg/mL
Hemolytic Cytotoxic
<5% Hemolysis | 800 | µg/mL | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Design, synthesis, and evaluation of the self-assembled antimicrobial peptides based on the ovalbumin-derived peptide TK913. | J Pept Sci | 2022
Evidence 3 Activity

Activity

% Hemolysis
Toxicity
10 %
Hemolytic Cytotoxic
Hemolytic_activity: Mouse erythrocytes: 10% Hemolysis=1660µg/ml | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
J Pept Sci. 2020 Oct 26(10):e3276.