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Peptide record

TPDB06397

Antibacterial Antifungal Hemolysis Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB06397
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 11-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
DAACAAHCLWR
Physicochemical Analysis
C51H77N17O14S2
NEQGIKMFPSTYV
A
1216.40
7.00
2
1
6
+0
-0.57
0.355
71.82
Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour
5625
462.43
2
Residue Composition
number
4
A
1
R
0
N
1
D
2
C
0
E
0
Q
0
G
1
H
0
I
1
L
0
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 4 R: 1 N: 0 D: 1 C: 2 E: 0 Q: 0 G: 0 H: 1 I: 0 L: 1 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
11
C51H77N17O14S2
1216.40
7.00
+0
-0.57
0.355
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>200 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >200 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Design and synthesis of cyclic disulfide-bonded antibacterial peptides on the basis of the alpha helical domain of Tenecin 1, an insect defensin. | Bioorg Med Chem | 2008
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis