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Peptide record

TPDB06395

Antibacterial Antifungal standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB06395
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 Peptipedia Antifungipept
standard
No
A 11-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, Peptipedia, and Antifungipept, with an available 3D structural model.
Sequence
FISQIISTARI
Physicochemical Analysis
C57H97N15O16
NDCEGHLKMPWYV
I
1248.49
11.05
1
0
6
+1
-0.75
1.118
150.91
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
4
Residue Composition
number
1
A
1
R
0
N
0
D
0
C
0
E
1
Q
0
G
0
H
4
I
0
L
0
K
0
M
1
F
0
P
2
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 4 L: 0 K: 0 M: 0 F: 1 P: 0 S: 2 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
11
C57H97N15O16
1248.49
11.05
+1
-0.75
1.118
Evidence Records 6 records
Evidence 1 Activity

Activity

MIC
Antibacterial
0.25 µg/mL

Target

Staphylococcus aureus MSSA or MRSA

Source & Reference

NA

Other

Active against primarily Gram-positive bacteria, including S. aureus MSSA or MRSA (MIC 0.25 ug/ml), E. faecalis (MIC 0.5 ug/ml) (anti-VRE), penicillin-resistant S. pneumoniae (MIC 32 ug/ml
Evidence 2 Activity

Activity

MIC
Antibacterial
0.5 µg/mL

Target

Enterococcus faecalis

Source & Reference

NA

Other

inst primarily Gram-positive bacteria, including S. aureus MSSA or MRSA (MIC 0.25 ug/ml), E. faecalis (MIC 0.5 ug/ml) (anti-VRE), penicillin-resistant S. pneumoniae (MIC 32 ug/ml), and K-pneumoniae (MIC >32
Evidence 3 Activity

Activity

MIC
Antibacterial
32 µg/mL

Target

S. pneumoniae

Source & Reference

NA

Other

SA or MRSA (MIC 0.25 ug/ml), E. faecalis (MIC 0.5 ug/ml) (anti-VRE), penicillin-resistant S. pneumoniae (MIC 32 ug/ml), and K-pneumoniae (MIC >32 ug/ml).
Evidence 4 Activity

Activity

MIC
Antifungal
0.25 µg/mL

Target

Staphylococcus aureus MSSA or MRSA

Source & Reference

Antifungipept

Other

Active against primarily Gram-positive bacteria, including S. aureus MSSA or MRSA (MIC 0.25 ug/ml), E. faecalis (MIC 0.5 ug/ml) (anti-VRE), penicillin-resistant S. pneumoniae (MIC 32 ug/ml
Evidence 5 Activity

Activity

MIC
Antifungal
0.5 µg/mL

Target

Enterococcus faecalis

Source & Reference

Antifungipept

Other

inst primarily Gram-positive bacteria, including S. aureus MSSA or MRSA (MIC 0.25 ug/ml), E. faecalis (MIC 0.5 ug/ml) (anti-VRE), penicillin-resistant S. pneumoniae (MIC 32 ug/ml), and K-pneumoniae (MIC >32
Evidence 6 Activity

Activity

MIC
Antifungal
32 µg/mL

Target

S. pneumoniae

Source & Reference

Antifungipept

Other

SA or MRSA (MIC 0.25 ug/ml), E. faecalis (MIC 0.5 ug/ml) (anti-VRE), penicillin-resistant S. pneumoniae (MIC 32 ug/ml), and K-pneumoniae (MIC >32 ug/ml).