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Peptide record

TPDB06394

Antibacterial Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB06394
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia
standard
No
A 11-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, dbAMP, and Peptipedia, with an available 3D structural model.
Sequence
CWWKKKKKWWC
Physicochemical Analysis
C80H112N20O12S2
ARNDEQGHILMFPSTYV
K
1610.02
10.39
5
0
4
+5
-2.93
-1.645
0.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
22125
1374.21
2
Residue Composition
number
0
A
0
R
0
N
0
D
2
C
0
E
0
Q
0
G
0
H
0
I
0
L
5
K
0
M
0
F
0
P
0
S
0
T
4
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 5 M: 0 F: 0 P: 0 S: 0 T: 0 W: 4 Y: 0 V: 0
Chemical Descriptors
11
C80H112N20O12S2
1610.02
10.39
+5
-2.93
-1.645
Evidence Records 1 records
Evidence 1 Activity

Activity

<5% Hemolysis
Toxicity
250 µg/mL
Hemolytic Cytotoxic
<5% Hemolysis | 250 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Design, crystal structure and atomic force microscopy study of thioether ligated d,l-cyclic antimicrobial peptides against multidrug resistant Pseudomonas aeruginosa. | Chem Sci | 2017