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Peptide record

TPDB06381

Antibacterial Antifungal Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB06381
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb
standard
No
A 11-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GRRRRSVQWCA
Physicochemical Analysis
C56H95N25O14S1
NDEHILKMFPTY
R
1374.59
12.40
4
0
3
+4
1.77
-1.373
35.45
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
400.12
3
Residue Composition
number
1
A
4
R
0
N
0
D
1
C
0
E
1
Q
1
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
1
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 4 N: 0 D: 0 C: 1 E: 0 Q: 1 G: 1 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
11
C56H95N25O14S1
1374.59
12.40
+4
1.77
-1.373
Evidence Records 5 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against S. aureus, L. monocytogenes, E. coli, and K. pneumoniae.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against S. aureus, L. monocytogenes, E. coli, and K. pneumoniae.
Evidence 3 Activity

Activity

5% Hemolysis
Toxicity
>512 µg/mL
Hemolytic Cytotoxic
5% Hemolysis | >512 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Influence of Dimerization of Lipopeptide Laur-Orn-Orn-Cys-NH2 and an N-terminal Peptide of Human Lactoferricin on Biological Activity. | Int J Pept Res Ther | 2015
Evidence 4 Activity

Activity

5% Hemolysis
Toxicity
128 µg/mL
Hemolytic Cytotoxic
5% Hemolysis | 128 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Influence of Dimerization of Lipopeptide Laur-Orn-Orn-Cys-NH2 and an N-terminal Peptide of Human Lactoferricin on Biological Activity. | Int J Pept Res Ther | 2015
Evidence 5 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Human antimicrobial peptides' antifungal activity against Aspergillus fumigatus. | Eur J Clin Microbiol Infect Dis | 2008