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Peptide record

TPDB06371

Antibacterial Antifungal Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB06371
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP ToxinPred 3.0
standard
No
A 11-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
FLPIIGKLLSG
Physicochemical Analysis
C57H96N12O13
ARNDCEQHMTWYV
L
1157.46
10.10
1
0
6
+1
-1.84
1.464
177.27
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
2
I
3
L
1
K
0
M
1
F
1
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 2 L: 3 K: 1 M: 0 F: 1 P: 1 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
11
C57H96N12O13
1157.46
10.10
+1
-1.84
1.464
Evidence Records 23 records
Evidence 1 Activity

Activity

MIC
Antibacterial
2.5 µM

Target

Staphylococcus aureus ATCC25923

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against Gram-positive S. aureus ATCC25923 (MIC 2.5 uM), E. faecalis ATCC29212 (MIC 20 uM), S. aureus IS 10# (MIC 10 uM), S. aureus IS 37# (MIC 5
Evidence 2 Activity

Activity

MIC
Antibacterial
20 µM

Target

Enterococcus faecalis ATCC29212

Source & Reference

dbAMP

Other

Active against Gram-positive S. aureus ATCC25923 (MIC 2.5 uM), E. faecalis ATCC29212 (MIC 20 uM), S. aureus IS 10# (MIC 10 uM), S. aureus IS 37# (MIC 5 uM), Gram-negative E. coli ATCC259
Evidence 3 Activity

Activity

MIC
Antibacterial
5 µM

Target

Escherichia coli ATCC25922

Source & Reference

dbAMP

Other

212 (MIC 20 uM), S. aureus IS 10# (MIC 10 uM), S. aureus IS 37# (MIC 5 uM), Gram-negative E. coli ATCC25922 (MIC 5 uM), E. cloacae ATCC13047 (MIC 2.5 uM), K. pneumoniae ATCC700603 (MIC 10 uM), B. pyocyaneus C
Evidence 4 Activity

Activity

MIC
Antibacterial
2.5 µM

Target

Enterobacter cloacae ATCC13047

Source & Reference

dbAMP

Other

10# (MIC 10 uM), S. aureus IS 37# (MIC 5 uM), Gram-negative E. coli ATCC25922 (MIC 5 uM), E. cloacae ATCC13047 (MIC 2.5 uM), K. pneumoniae ATCC700603 (MIC 10 uM), B. pyocyaneus CMCCB1010 (MIC 20 uM), P. aeruginosa
Evidence 5 Activity

Activity

MIC
Antibacterial
10 µM

Target

Klebsiella pneumoniae ATCC700603

Source & Reference

dbAMP

Other

MIC 5 uM), Gram-negative E. coli ATCC25922 (MIC 5 uM), E. cloacae ATCC13047 (MIC 2.5 uM), K. pneumoniae ATCC700603 (MIC 10 uM), B. pyocyaneus CMCCB1010 (MIC 20 uM), P. aeruginosa ATCC27853 (MIC 5 uM), B. dysenteriae
Evidence 6 Activity

Activity

MIC
Antibacterial
20 µM

Target

B. pyocyaneus CMCCB1010

Source & Reference

dbAMP

Other

5922 (MIC 5 uM), E. cloacae ATCC13047 (MIC 2.5 uM), K. pneumoniae ATCC700603 (MIC 10 uM), B. pyocyaneus CMCCB1010 (MIC 20 uM), P. aeruginosa ATCC27853 (MIC 5 uM), B. dysenteriae (MIC 5 uM), E. coli IS 37# (MIC 20 uM
Evidence 7 Activity

Activity

MIC
Antibacterial
5 µM

Target

Pseudomonas aeruginosa ATCC27853

Source & Reference

dbAMP

Other

(MIC 2.5 uM), K. pneumoniae ATCC700603 (MIC 10 uM), B. pyocyaneus CMCCB1010 (MIC 20 uM), P. aeruginosa ATCC27853 (MIC 5 uM), B. dysenteriae (MIC 5 uM), E. coli IS 37# (MIC 20 uM), E. coli IS 117# (MIC 5 uM), E. co
Evidence 8 Activity

Activity

MIC
Antibacterial
5 µM

Target

B. dysenteriae

Source & Reference

dbAMP

Other

603 (MIC 10 uM), B. pyocyaneus CMCCB1010 (MIC 20 uM), P. aeruginosa ATCC27853 (MIC 5 uM), B. dysenteriae (MIC 5 uM), E. coli IS 37# (MIC 20 uM), E. coli IS 117# (MIC 5 uM), E. coli IS 218# (MIC 20 uM), P.
Evidence 9 Activity

Activity

MIC
Antibacterial
10 µM

Target

Candida albicans ATCC2002

Source & Reference

dbAMP

Other

# (MIC 20 uM), P. aeruginosa IS 350# (MIC 10 uM), K. pneumoniae IS 59# (MIC 80 uM), fungi C. albicans ATCC2002 (MIC 10 uM), C. albicans ATCC90028 (MIC 10 uM), and C. parapsilosis ATCC22019 (MIC 2.5 uM). Updated 7
Evidence 10 Activity

Activity

MIC
Antibacterial
10 µM

Target

Candida albicans ATCC90028

Source & Reference

dbAMP

Other

0# (MIC 10 uM), K. pneumoniae IS 59# (MIC 80 uM), fungi C. albicans ATCC2002 (MIC 10 uM), C. albicans ATCC90028 (MIC 10 uM), and C. parapsilosis ATCC22019 (MIC 2.5 uM). Updated 7/2021
Evidence 11 Activity

Activity

MIC
Antibacterial
2.5 µM

Target

C. parapsilosis ATCC22019

Source & Reference

dbAMP

Other

IC 80 uM), fungi C. albicans ATCC2002 (MIC 10 uM), C. albicans ATCC90028 (MIC 10 uM), and C. parapsilosis ATCC22019 (MIC 2.5 uM). Updated 7/2021
Evidence 12 Activity

Activity

MIC
Antifungal
2.5 µM

Target

Staphylococcus aureus ATCC25923

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against Gram-positive S. aureus ATCC25923 (MIC 2.5 uM), E. faecalis ATCC29212 (MIC 20 uM), S. aureus IS 10# (MIC 10 uM), S. aureus IS 37# (MIC 5
Evidence 13 Activity

Activity

MIC
Antifungal
20 µM

Target

Enterococcus faecalis ATCC29212

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against Gram-positive S. aureus ATCC25923 (MIC 2.5 uM), E. faecalis ATCC29212 (MIC 20 uM), S. aureus IS 10# (MIC 10 uM), S. aureus IS 37# (MIC 5 uM), Gram-negative E. coli ATCC259
Evidence 14 Activity

Activity

MIC
Antifungal
5 µM

Target

Escherichia coli ATCC25922

Source & Reference

dbAMP CAFPdb Antifungipept

Other

212 (MIC 20 uM), S. aureus IS 10# (MIC 10 uM), S. aureus IS 37# (MIC 5 uM), Gram-negative E. coli ATCC25922 (MIC 5 uM), E. cloacae ATCC13047 (MIC 2.5 uM), K. pneumoniae ATCC700603 (MIC 10 uM), B. pyocyaneus C
Evidence 15 Activity

Activity

MIC
Antifungal
2.5 µM

Target

Enterobacter cloacae ATCC13047

Source & Reference

dbAMP CAFPdb Antifungipept

Other

10# (MIC 10 uM), S. aureus IS 37# (MIC 5 uM), Gram-negative E. coli ATCC25922 (MIC 5 uM), E. cloacae ATCC13047 (MIC 2.5 uM), K. pneumoniae ATCC700603 (MIC 10 uM), B. pyocyaneus CMCCB1010 (MIC 20 uM), P. aeruginosa
Evidence 16 Activity

Activity

MIC
Antifungal
10 µM

Target

Klebsiella pneumoniae ATCC700603

Source & Reference

dbAMP CAFPdb Antifungipept

Other

MIC 5 uM), Gram-negative E. coli ATCC25922 (MIC 5 uM), E. cloacae ATCC13047 (MIC 2.5 uM), K. pneumoniae ATCC700603 (MIC 10 uM), B. pyocyaneus CMCCB1010 (MIC 20 uM), P. aeruginosa ATCC27853 (MIC 5 uM), B. dysenteriae
Evidence 17 Activity

Activity

MIC
Antifungal
20 µM

Target

B. pyocyaneus CMCCB1010

Source & Reference

dbAMP CAFPdb Antifungipept

Other

5922 (MIC 5 uM), E. cloacae ATCC13047 (MIC 2.5 uM), K. pneumoniae ATCC700603 (MIC 10 uM), B. pyocyaneus CMCCB1010 (MIC 20 uM), P. aeruginosa ATCC27853 (MIC 5 uM), B. dysenteriae (MIC 5 uM), E. coli IS 37# (MIC 20 uM
Evidence 18 Activity

Activity

MIC
Antifungal
5 µM

Target

Pseudomonas aeruginosa ATCC27853

Source & Reference

dbAMP CAFPdb Antifungipept

Other

(MIC 2.5 uM), K. pneumoniae ATCC700603 (MIC 10 uM), B. pyocyaneus CMCCB1010 (MIC 20 uM), P. aeruginosa ATCC27853 (MIC 5 uM), B. dysenteriae (MIC 5 uM), E. coli IS 37# (MIC 20 uM), E. coli IS 117# (MIC 5 uM), E. co
Evidence 19 Activity

Activity

MIC
Antifungal
5 µM

Target

B. dysenteriae

Source & Reference

dbAMP CAFPdb Antifungipept

Other

603 (MIC 10 uM), B. pyocyaneus CMCCB1010 (MIC 20 uM), P. aeruginosa ATCC27853 (MIC 5 uM), B. dysenteriae (MIC 5 uM), E. coli IS 37# (MIC 20 uM), E. coli IS 117# (MIC 5 uM), E. coli IS 218# (MIC 20 uM), P.
Evidence 20 Activity

Activity

MIC
Antifungal
10 µM

Target

Candida albicans ATCC2002

Source & Reference

dbAMP CAFPdb Antifungipept

Other

# (MIC 20 uM), P. aeruginosa IS 350# (MIC 10 uM), K. pneumoniae IS 59# (MIC 80 uM), fungi C. albicans ATCC2002 (MIC 10 uM), C. albicans ATCC90028 (MIC 10 uM), and C. parapsilosis ATCC22019 (MIC 2.5 uM). Updated 7
Evidence 21 Activity

Activity

MIC
Antifungal
10 µM

Target

Candida albicans ATCC90028

Source & Reference

dbAMP CAFPdb Antifungipept

Other

0# (MIC 10 uM), K. pneumoniae IS 59# (MIC 80 uM), fungi C. albicans ATCC2002 (MIC 10 uM), C. albicans ATCC90028 (MIC 10 uM), and C. parapsilosis ATCC22019 (MIC 2.5 uM). Updated 7/2021
Evidence 22 Activity

Activity

MIC
Antifungal
2.5 µM

Target

C. parapsilosis ATCC22019

Source & Reference

dbAMP CAFPdb Antifungipept

Other

IC 80 uM), fungi C. albicans ATCC2002 (MIC 10 uM), C. albicans ATCC90028 (MIC 10 uM), and C. parapsilosis ATCC22019 (MIC 2.5 uM). Updated 7/2021
Evidence 23 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial peptides from the venom gland of the social wasp Vespa tropica. | Toxicon | 2013