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Peptide record

TPDB06310

Antibacterial Antifungal Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB06310
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 11-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
GKLFKKILKIL
Physicochemical Analysis
C65H117N15O12
ARNDCEQHMPSTWYV
K
1300.74
11.00
4
0
6
+4
0.54
0.655
177.27
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
2
I
3
L
4
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 2 L: 3 K: 4 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
11
C65H117N15O12
1300.74
11.00
+4
0.54
0.655
Evidence Records 11 records
Evidence 1 Activity

Activity

MIC
Antibacterial
3.1 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
active against Gram- E. coli (MIC 3.1 ug/ml), P. aeruginosa (MIC 12.5 ug/ml), Gram+ S. aeurus (MIC 12.5 ug/ml), fungi C. albicans (MIC
Evidence 2 Activity

Activity

MIC
Antibacterial
12.5 µg/mL

Target

Pseudomonas aeruginosa

Source & Reference

dbAMP

Other

active against Gram- E. coli (MIC 3.1 ug/ml), P. aeruginosa (MIC 12.5 ug/ml), Gram+ S. aeurus (MIC 12.5 ug/ml), fungi C. albicans (MIC 3.1 ug/ml), and F. solani (MIC
Evidence 3 Activity

Activity

MIC
Antibacterial
12.5 µg/mL

Target

S. aeurus

Source & Reference

dbAMP

Other

active against Gram- E. coli (MIC 3.1 ug/ml), P. aeruginosa (MIC 12.5 ug/ml), Gram+ S. aeurus (MIC 12.5 ug/ml), fungi C. albicans (MIC 3.1 ug/ml), and F. solani (MIC 12.5 ug/ml).
Evidence 4 Activity

Activity

MIC
Antibacterial
3.1 µg/mL

Target

Candida albicans

Source & Reference

dbAMP

Other

(MIC 3.1 ug/ml), P. aeruginosa (MIC 12.5 ug/ml), Gram+ S. aeurus (MIC 12.5 ug/ml), fungi C. albicans (MIC 3.1 ug/ml), and F. solani (MIC 12.5 ug/ml).
Evidence 5 Activity

Activity

MIC
Antibacterial
12.5 µg/mL

Target

F. solani

Source & Reference

dbAMP

Other

MIC 12.5 ug/ml), Gram+ S. aeurus (MIC 12.5 ug/ml), fungi C. albicans (MIC 3.1 ug/ml), and F. solani (MIC 12.5 ug/ml).
Evidence 6 Activity

Activity

MIC
Antifungal
3.1 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
active against Gram- E. coli (MIC 3.1 ug/ml), P. aeruginosa (MIC 12.5 ug/ml), Gram+ S. aeurus (MIC 12.5 ug/ml), fungi C. albicans (MIC
Evidence 7 Activity

Activity

MIC
Antifungal
12.5 µg/mL

Target

Pseudomonas aeruginosa

Source & Reference

dbAMP CAFPdb Antifungipept

Other

active against Gram- E. coli (MIC 3.1 ug/ml), P. aeruginosa (MIC 12.5 ug/ml), Gram+ S. aeurus (MIC 12.5 ug/ml), fungi C. albicans (MIC 3.1 ug/ml), and F. solani (MIC
Evidence 8 Activity

Activity

MIC
Antifungal
12.5 µg/mL

Target

S. aeurus

Source & Reference

dbAMP CAFPdb Antifungipept

Other

active against Gram- E. coli (MIC 3.1 ug/ml), P. aeruginosa (MIC 12.5 ug/ml), Gram+ S. aeurus (MIC 12.5 ug/ml), fungi C. albicans (MIC 3.1 ug/ml), and F. solani (MIC 12.5 ug/ml).
Evidence 9 Activity

Activity

MIC
Antifungal
3.1 µg/mL

Target

Candida albicans

Source & Reference

dbAMP CAFPdb Antifungipept

Other

(MIC 3.1 ug/ml), P. aeruginosa (MIC 12.5 ug/ml), Gram+ S. aeurus (MIC 12.5 ug/ml), fungi C. albicans (MIC 3.1 ug/ml), and F. solani (MIC 12.5 ug/ml).
Evidence 10 Activity

Activity

MIC
Antifungal
12.5 µg/mL

Target

F. solani

Source & Reference

dbAMP CAFPdb Antifungipept

Other

MIC 12.5 ug/ml), Gram+ S. aeurus (MIC 12.5 ug/ml), fungi C. albicans (MIC 3.1 ug/ml), and F. solani (MIC 12.5 ug/ml).
Evidence 11 Activity

Activity

50% Hemolysis
Toxicity
400 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 400 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Novel short antibacterial and antifungal peptides with low cytotoxicity: Efficacy and action mechanisms. | Biochem Biophys Res Commun | 2010