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Peptide record

TPDB06303

Antibacterial Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB06303
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 11-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
KWLRWVRRRWW
Physicochemical Analysis
C85H122N28O12
ANDCEQGHIMFPSTY
RW
1728.08
12.88
5
0
6
+5
-3.66
-1.591
61.82
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
22000
1273.09
0
Residue Composition
number
0
A
4
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
1
L
1
K
0
M
0
F
0
P
0
S
0
T
4
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 1 M: 0 F: 0 P: 0 S: 0 T: 0 W: 4 Y: 0 V: 1
Chemical Descriptors
11
C85H122N28O12
1728.08
12.88
+5
-3.66
-1.591
Evidence Records 2 records
Evidence 1 Activity

Activity

46.2% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
46.2% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Design, Synthesis, and Antimicrobial Activities of Novel Functional Peptides Against Gram-positive and Gram-negative Bacteria. | Chem Biol Drug Des | 2019
Evidence 2 Activity

Activity

3% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
3% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
NOVEL PEPTIDE AND USES THEREOF | Patent US 20160130301 A1 | 2016