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Peptide record

TPDB06296

Antibacterial Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB06296
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 11-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
KLWLLWLKWLL
Physicochemical Analysis
C81H122N16O12
ARNDCEQGHIMFPSTYV
L
1511.96
10.60
2
0
9
+2
-6.93
1.118
212.73
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
16500
1091.30
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
6
L
2
K
0
M
0
F
0
P
0
S
0
T
3
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 6 K: 2 M: 0 F: 0 P: 0 S: 0 T: 0 W: 3 Y: 0 V: 0
Chemical Descriptors
11
C81H122N16O12
1511.96
10.60
+2
-6.93
1.118
Evidence Records 1 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
1.56 µM
Hemolytic Cytotoxic
5% Hemolysis | 1.56 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Cell specificity, anti-inflammatory activity, and plausible bactericidal mechanism of designed Trp-rich model antimicrobial peptides | Biochim Biophys Acta | 2009