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Peptide record

TPDB06275

Antibacterial Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB06275
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia
standard
No
A 11-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
VWRRWRRFWRR
Physicochemical Analysis
C83H122N32O12
ANDCEQGHILKMPSTY
R
1760.09
13.10
6
0
5
+6
-1.75
-2.064
26.36
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
16500
937.45
0
Residue Composition
number
0
A
6
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
1
F
0
P
0
S
0
T
3
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 6 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 3 Y: 0 V: 1
Chemical Descriptors
11
C83H122N32O12
1760.09
13.10
+6
-1.75
-2.064
Evidence Records 3 records
Evidence 1 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-activity analysis and biological studies of chensinin-1b analogues. | Acta Biomater | 2016
Evidence 2 Activity

Activity

1.2% Hemolysis
Toxicity
500 µM
Hemolytic Cytotoxic
1.2% Hemolysis | 500 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial Activity, Membrane Interaction and Stability of the D-amino Acid Substituted Analogs of Antimicrobial Peptide W3R6. | J Photochem Photobiol B | 2019
Evidence 3 Activity

Activity

HC50
Toxicity
500 µM
Hemolytic
Hemolytic_activity: [Ref.27060618] HC50>500µM against human red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Acta Biomater. 2016 Jun 37:59-68.